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pDONR223_TP53_p.I195F

Plasmid

#81395

Purpose

Gateway Donor vector containing TP53 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

TP53 (TP53 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

P72R; I195F; P278A

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_EDNRB_p.F292L

Plasmid

#81402

Purpose

Gateway Donor vector containing EDNRB , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

EDNRB (EDNRB Human)

Use

Gateway entry vector

Tags

Expression

Mutation

F292L

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_BECN1_WT

Plasmid

#82100

Purpose

Gateway Donor vector containing BECN1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

BECN1 (BECN1 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

A103V

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pXPR_BRD003-sgWRN3

Plasmid

#125773

Purpose

constitutive expression of a guide RNA targeting human WRN

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

sgWRN3 (WRN Human)

Use

CRISPR

Tags

Expression

Mutation

Promoter

Available since

June 11, 2019

Availability

Academic Institutions and Nonprofits only

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pDONR223_PTEN_p.R173H

Plasmid

#81682

Purpose

Gateway Donor vector containing PTEN, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

PTEN (PTEN Human)

Use

Gateway entry vector

Tags

Expression

Mutation

R173H

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_CPZ_WT

Plasmid

#81884

Purpose

Gateway Donor vector containing CPZ , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

CPZ (CPZ Human)

Use

Gateway entry vector

Tags

Expression

Mutation

T63M

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_CCNG1_p.E167K

Plasmid

#81326

Purpose

Gateway Donor vector containing CCNG1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

CCNG1 (CCNG1 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

E167K

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pVZ_PcoaT_SQE1

Plasmid

#103860

Purpose

Heterologous, cobalt-inducible expression of SQE1 from A. thaliana in Synechocystis sp. PCC6803

Depositor

Ilka Axmann

Article

Loeschcke et al PLoS One. 2017 Dec 27;12(12):e0189816. d

Insert

squalene epoxidase 1 (XF1 Mustard Weed)

Use

Synthetic Biology

Tags

Expression

Bacterial

Mutation

inserted gene is codon optimized. 2nd amino acid …

Promoter

PcoaT (from Synechocystis sp. PCC 6803)

Available since

Jan. 23, 2018

Availability

Academic Institutions and Nonprofits only

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pDONR223_ACVR2A_p.A381V

Plasmid

#81476

Purpose

Gateway Donor vector containing ACVR2A , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

ACVR2A (ACVR2A Human)

Use

Gateway entry vector

Tags

Expression

Mutation

A381V

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_ACVR1B_p.D335N

Plasmid

#81438

Purpose

Gateway Donor vector containing ACVR1B , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

ACVR1B (ACVR1B Human)

Use

Gateway entry vector

Tags

Expression

Mutation

D335N

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_ACVR1B_p.E412D

Plasmid

#81447

Purpose

Gateway Donor vector containing ACVR1B , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

ACVR1B (ACVR1B Human)

Use

Gateway entry vector

Tags

Expression

Mutation

E412D

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag NME7

Plasmid

#20509

Depositor

Jean Zhao, William Hahn

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

NME7 (NME7 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Mutation

Promoter

Available since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only
pDONR223_C15orf23_WT

Plasmid

#81896

Purpose

Gateway Donor vector containing C15ORF23 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

C15ORF23 (KNSTRN Human)

Use

Gateway entry vector

Tags

Expression

Mutation

A40E; R75L; P92S; S232G

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_ACTG1_p.K61E

Plasmid

#81397

Purpose

Gateway Donor vector containing ACTG1 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

ACTG1 (ACTG1 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

K61E; H88Y; p.374_375delCF-insSS

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_MAP2K1_p.P124S

Plasmid

#81703

Purpose

Gateway Donor vector containing MAP2K1, part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

MAP2K1 (MAP2K1 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

P124S; I310N

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_GATA3_p.S118F

Plasmid

#81465

Purpose

Gateway Donor vector containing GATA3 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

GATA3 (GATA3 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

V3A; S118F

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_ILKAP_p.S61Y

Plasmid

#81376

Purpose

Gateway Donor vector containing ILKAP , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

ILKAP (ILKAP Human)

Use

Gateway entry vector

Tags

Expression

Mutation

S61Y

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_CD70_p.D165Y

Plasmid

#81603

Purpose

Gateway Donor vector containing CD70 , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

CD70 (CD70 Human)

Use

Gateway entry vector

Tags

Expression

Mutation

D165Y

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pDONR223_CTCF_p.R377H

Plasmid

#81566

Purpose

Gateway Donor vector containing CTCF , part of the Target Accelerator Plasmid Collection.

Depositor

Jesse Boehm, William Hahn, David Root

Article

Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

Insert

CTCF (CTCF Human)

Use

Gateway entry vector

Tags

Expression

Mutation

R377H

Promoter

None

Available since

April 24, 2017

Availability

Academic Institutions and Nonprofits only

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pWZL Neo Myr Flag ADCK4

Plasmid

#20544

Depositor

Jean Zhao, William Hahn

Article

Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

Insert

ADCK4 (ADCK4 Human)

Use

Retroviral

Tags

Flag and Myr

Expression

Mammalian

Mutation

Promoter

Available since

Oct. 27, 2009

Availability

Academic Institutions and Nonprofits only