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Plasmid#118622Purposeexpression of mChe-tagged cdc42E7-E6-3'UTR under pSyn promoter for primary neuronsDepositorInsertcdc42E7-E6 3'UTR (Cdc42 Mouse)
UseLentiviralTagsmCherryExpressionMammalianMutationchanged ttgcttt to cggtaag (496 - 502 nt in 3…Promotersynapsin I (rat)Available sinceMarch 28, 2019AvailabilityAcademic Institutions and Nonprofits only -
ERBB4 gRNA (BRDN0001162324)
Plasmid#76198Purpose3rd generation lentiviral gRNA plasmid targeting human ERBB4DepositorInsertERBB4 (ERBB4 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
pU6-crRNA(TBK1)
Plasmid#109322PurposeAAV vector expressing crRNA for AsCpf1 (RR variant) targeting human TBK1DepositorInsertmCherry-KASH (TBK1 Human)
UseAAVTagsExpressionMutationPromoterhSynAvailable sinceApril 30, 2018AvailabilityAcademic Institutions and Nonprofits only -
pCAG_SRGAP2A_GAP(R527L_K566A)
Plasmid#222617PurposeExpresses full length SRGAP2 with R527L, K566A mt in the Rac1-specific GAP domain that abrogates the GTPase activating function of SRGAP2 without locking the GAP-domain in a form bound to Rac1-GDP.DepositorInsertSRGAP2 (SRGAP2 Human)
UseTagsEGFPExpressionMammalianMutationPoint mutations R527L and K566A (Rac1-specific GA…PromoterAvailable sinceOct. 9, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLenti HsATP13A2 WT (PAM) _ Hygro
Plasmid#213697Purposetransfer plasmid for lentiviral vector production expressing Hs ATP13A2 WTDepositorInserthuman ATP13A2 WT PAM (ATP13A2 Human)
UseLentiviralTagsExpressionMutationWT, D508NPromoterCMVAvailable sinceAug. 20, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV-Syn1-DIO-Snca (human A53T)
Plasmid#214201PurposeFor Cre-dependent expression of alpha synuclein (human gene containing A53T mutation)DepositorInsertSnca (A53T) (SNCA Human)
UseAAV and Cre/LoxTagsExpressionMammalianMutationA53TPromoterAvailable sinceMarch 29, 2024AvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR v2-sgABI2-1
Plasmid#210139Purposeknock out ABI2 in mammalian cellsDepositorInsertAbl interactor 2 (ABI2 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceNov. 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR v2-sgCYFIP1-1
Plasmid#210137Purposeknock out CYFIP1 in mammalian cellsDepositorInsertCytoplasmic FMR1-interacting protein 1 (CYFIP1 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceNov. 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR v2-sgABI2-2
Plasmid#210140Purposeknock out ABI2 in mammalian cellsDepositorInsertAbl interactor 2 (ABI2 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceNov. 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR v2-sgHSPC300-1
Plasmid#210141Purposeknock out HSPC300 in mammalian cellsDepositorInsertProtein BRICK1 (BRK1 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceNov. 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR v2-sgHSPC300-2
Plasmid#210142Purposeknock out HSPC300 in mammalian cellsDepositorInsertProtein BRICK1 (BRK1 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceNov. 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
lentiCRISPR v2-sgCYFIP1-2
Plasmid#210138Purposeknock out CYFIP1 in mammalian cellsDepositorInsertCytoplasmic FMR1-interacting protein 1 (CYFIP1 Human)
UseCRISPRTagsExpressionMutationPromoterAvailable sinceNov. 8, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GRAB_CRF0.5
Plasmid#208657PurposeExpresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5 in neuronsDepositorInsertGPCR activation based corticotropin-releasing factor (CRF) sensor GRAB_CRF0.5
UseAAVTagsExpressionMutationPromoterhSynAvailable sinceOct. 23, 2023AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GRAB_CRFmut
Plasmid#208659PurposeExpresses the genetically-encoded fluorescent corticotropin-releasing factor (CRF) control sensor GRAB_CRFmut in neuronsDepositorInsertGPCR activation based corticotropin-releasing factor (CRF) contorl sensor GRAB_CRFmut
UseAAVTagsExpressionMutationPromoterhSynAvailable sinceOct. 13, 2023AvailabilityAcademic Institutions and Nonprofits only -
pTol2CG NBT:NRGIIIa_R551Q:polyA
Plasmid#193013PurposeTol2 transgenic construct that will express human Neuregulin1 Type IIIa R551Q patient variant in neuronsDepositorInsertsUseTransposon transgenesisTagsExpressionMammalianMutationENST00000287842, NM_013956, c.1652G>A, p.(Arg5…PromoterAvailable sinceDec. 13, 2022AvailabilityAcademic Institutions and Nonprofits only -
W118-1_hZBTB7B_R363L
Plasmid#180381Purposelentiviral transduction of human ZBTB7B gene with a point mutation (R363L) in the first ZF domainDepositorInsertZBTB7B_R363L (ZBTB7B Human)
UseLentiviralTagsExpressionMammalianMutationR363LPromoterCMVAvailable sinceDec. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
W118-1_hZBTB7B_D35N_R49Q
Plasmid#180383Purposelentiviral transduction of human ZBTB7B gene with point mutations (D35N and R49Q) in the BTB domainDepositorInsertZBTB7B_D35N/R49Q (ZBTB7B Human)
UseLentiviralTagsExpressionMammalianMutationD35N/R49QPromoterCMVAvailable sinceDec. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
W118-1_hZBTB7B_R49H
Plasmid#180382Purposelentiviral transduction of human ZBTB7B gene with a point mutation (R49H) in the BTB domainDepositorInsertZBTB7B_R49H (ZBTB7B Human)
UseLentiviralTagsExpressionMammalianMutationR49HPromoterCMVAvailable sinceDec. 1, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-GFP-IRES-hSNCA (A11P/V70P)
Plasmid#185717PurposeAAV expression of GFP and human α-Synuclein with A11P and V70P mutations from hSyn promoterDepositorInsertsynuclein, alpha (SNCA Human)
UseAAVTagsExpressionMutationChanged Ala 11 to Pro, Val 70 to ProPromoterhSynAvailable sinceJune 28, 2022AvailabilityAcademic Institutions and Nonprofits only -
pCMV ShadowY-AURKA-mTurq2
Plasmid#157770PurposeExpression of AuroraA kinase biosensor under CMV promoterDepositorInsertAURKA (AURKA Human)
UseTagsmTurquoise2 and shadowYExpressionMammalianMutationPromoterCMVAvailable sinceMarch 9, 2021AvailabilityAcademic Institutions and Nonprofits only