We narrowed to 15,880 results for: grna

1. LentiU6-mHbb-bh1_ gRNA_1-MS2-Puro

   Plasmid

   #192681

   Purpose

   Lentiviral expression of sgRNA targeting mHbb-bh1promoter to activate mouse Hbb-bh1 transcription

   Depositor

   Jeffrey Miner

   Article

   Omachi et al PLoS One. 2022 Jun 28;17(6):e0270008. do

   Insert

   Mouse Hbb-bh1 activating gRNA #1 (Hbb-bh1 Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available Since

   Dec. 15, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLVX-CMV-XRCC1-gRNA res-Neo

   Plasmid

   #176149

   Purpose

   XRCC1 with dual PAM resistance to XRCC1 gRNA1 and XRCC1 gRNA2 & a neomycin/G418 resistance cassette

   Depositor

   Robert Sobol

   Article

   Koczor et al Cell Rep. 2021 Nov 2;37(5):109917. doi:

   Insert

   X-ray repair cross complementing 1 (XRCC1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Dual PAM resistance to XRCC1 gRNA 1 and XRCC1 gRN…

   Promoter

   CMV

   Available Since

   Jan. 27, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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3. pX458-Ef1a-Cas9-GFP (gRNA: Ascl1-3)

   Plasmid

   #159658

   Purpose

   CRISPR/Cas9 expressing plasmid containing the gRNA targeting mouse Ascl1.

   Depositor

   Joseph Brzezinski

   Article

   Kaufman et al Development. 2021 Jun 15;148(12). pii: 2

   Insert

   hSpCas9
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Ef1a

   Available Since

   March 22, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. pX458-Ef1a-Cas9-GFP (gRNA: Ascl1-2)

   Plasmid

   #159657

   Purpose

   CRISPR/Cas9 expressing plasmid containing the gRNA targeting mouse Ascl1.

   Depositor

   Joseph Brzezinski

   Article

   Kaufman et al Development. 2021 Jun 15;148(12). pii: 2

   Insert

   hSpCas9
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Ef1a

   Available Since

   March 22, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. pOTTC1270 - pAAV Rosa26 gRNA A+B EF1a EGFP

   Plasmid

   #113156

   Purpose

   An AAV vector that expresses guide RNAs targeting rat Rosa26 and expresses EGFP reporter

   Depositor

   Brandon Harvey

   Article

   Back et al Neuron. 2019 Feb 8. pii: S0896-6273(19)3

   Insert

   Two gRNAs for rat Rosa26
   

   Use

   AAV and CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   mU6 and hU6

   Available Since

   March 7, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. JJ802: pMAGIC (L1-R5) hU6::SaCas9 gRNA scaffold

   Plasmid

   #121812

   Purpose

   pMAGIC L1-R5 entry plasmid, contains empty human U6-driven SaCas9 gRNA scaffold for 4-component MultiSite Gateway Pro assembly. Protospacer motif can be inserted after BsaI digestion.

   Depositor

   Christopher Newgard

   Article

   Haldeman et al Nucleic Acids Res. 2018 Dec 27. pii: 526

   Type

   Empty backbone

   Use

   Synthetic Biology; Pmagic gateway entry plasmid

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pEG302 5aa SunTag VP64 gRNA4 (FWA)

   Plasmid

   #115481

   Purpose

   CRISPR-Cas9 SunTag system to target VP64 to the FWA locus with a single guide RNA

   Depositor

   Steven Jacobsen

   Article

   Papikian et al Nat Commun. 2019 Feb 13;10(1):729. doi:

   Insert

   g4_U6_NOS_NLS_GB1_NLS_linker_VP64_linker_sfGFP_scFv_UBQ10_Insulator_UBQ10_Ω_dCas9_1xHA_2xNLS_linker_10xGCN4_OCS
   

   Use

   CRISPR and Synthetic Biology

   Tags

   Expression

   Plant

   Mutation

   Promoter

   Available Since

   April 16, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pEG302 5aa SunTag VP64 gRNA17 (FWA)

   Plasmid

   #115482

   Purpose

   CRISPR-Cas9 SunTag system to target VP64 to the FWA locus with a single guide RNA

   Depositor

   Steven Jacobsen

   Article

   Papikian et al Nat Commun. 2019 Feb 13;10(1):729. doi:

   Insert

   g17_U6_NOS_NLS_GB1_NLS_linker_VP64_linker_sfGFP_scFv_UBQ10_Insulator_UBQ10_Ω_dCas9_1xHA_2xNLS_linker_10xGCN4_OCS
   

   Use

   CRISPR and Synthetic Biology

   Tags

   Expression

   Plant

   Mutation

   Promoter

   Available Since

   March 21, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLL6 sgRNA(MS2)-MS2-hA3a D131E

   Plasmid

   #112132

   Purpose

   empty sgRNA cloning vector with MS2-humanA3a D131E

   Depositor

   Fei-Long Meng

   Article

   Liu et al Cell Rep. 2018 Oct 23;25(4):884-892.e3.

   Insert

   human Apobec3a D131E mutant (APOBEC3A Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   D131E mutant in hA3a

   Promoter

   hU6,CBh

   Available Since

   Sept. 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. C-term AAV-SpCas9-VRQR-gRNA_entry (HES1477)

    Plasmid

    #242660

    Purpose

    CBh promoter expression plasmid for C-terminal intein-split AAV construct with C-term of SpCas9-VRQR and pU6 SpCas9 gRNA entry cassette

    Depositor

    Benjamin Kleinstiver

    Insert

    pAAV-pCbh-BPNLS-NpuC-SpCas9-VRQR-BPNLS-WPRE-bGH_PA-SpCas9_gRNA_entrycassette
    

    Use

    AAV and CRISPR

    Tags

    BPNLS

    Expression

    Mutation

    VRQR mutations in SpCas9(S55R/D1135V/G1218R/R1335…

    Promoter

    CBh

    Available Since

    Oct. 9, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pYJ29-lenti-U6-SOX17-acti-gRNA-DsRed

    Plasmid

    #131072

    Purpose

    Activation of SOX17 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    SOX17 activation gRNA (SOX17 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pYJ30-lenti-U6-MAFA-acti-gRNA1-MS2

    Plasmid

    #131073

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA1 (MAFA Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pYJ31-lenti-U6-MAFA-acti-gRNA2-MS2

    Plasmid

    #131074

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA2 (MAFA Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pYJ32-lenti-U6-MAFA-acti-gRNA3-MS2

    Plasmid

    #131075

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    MAFA activation gRNA3 (MAFA Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pYJ33-lenti-U6-Oct4-PE-acti-gRNA-DsRed

    Plasmid

    #131076

    Purpose

    Activation of Mafa via SAM system

    Depositor

    Xiaojun Lian

    Insert

    OCT4 proximal enhancer gRNA (POU5F1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. pYJ23-lenti-MS2-U6-NKX6.1-acti-gRNA1

    Plasmid

    #131067

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA1 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pYJ24-lenti-MS2-U6-NKX6.1-acti-gRNA2

    Plasmid

    #131068

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA2 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pYJ25-lenti-MS2-U6-NKX6.1-acti-gRNA3

    Plasmid

    #131069

    Purpose

    Activation of NKX6.1 via SAM system

    Depositor

    Xiaojun Lian

    Insert

    NKX6.1 activation gRNA3 (NKX6-1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    Oct. 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. sgRNA-Dual_filler(hU6_H1/7SK hybrid)-EF1as_Thy1.1_P2A_Neo

    Plasmid

    #239609

    Purpose

    Backbone for the cloning of a dual sgRNA expression plasmid (hU6 and minimal H1/7SK hybrid promoters) using BsmbI. Selectable with a G418 resistance

    Depositor

    Philipp Rathert

    Article

    Stadager et al Cell Rep Methods. 2025 Jun 16;5(6):10107

    Insert

    filler-trcr-H1/7SKhybrid-filler
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Sept. 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pAAV- GfaABC1D::Cas9-HA-sgRNA-Ezr-seq2

    Plasmid

    #240865

    Purpose

    GfaABC1D promoter driven HA-tagged SaCas9 together with U6 driven expression of sgRNA targeting exon-1 of mouse Ezrin; for knocking-out ezrin in murine astrocytes

    Depositor

    Mark Verheijen

    Article

    Badia-Soteras et al Biol Psychiatry. 2023 Aug 1;94(3):226-23

    Insert

    U6 driven sgRNA Targeting exon 1 of EZR (Ezr Mouse)
    

    Use

    AAV and CRISPR

    Tags

    SaCas9 + 3X HA-Tag

    Expression

    Mammalian

    Mutation

    Promoter

    GfaABC1D

    Available Since

    Aug. 22, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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