-
Plasmid#64622Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertNOTCH1 (NOTCH1 Human)
UseLentiviralTagsV5ExpressionMutationintracellular domain *PromoterPGKAvailable sinceNov. 30, 2015AvailabilityAcademic Institutions and Nonprofits only -
MEK5 DD(S311D,T315D)-pcw107-V5
Plasmid#64619Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertMAP2K5 (MAP2K5 Human)
UseLentiviralTagsV5ExpressionMutationS311D, T315D*PromoterPGKAvailable sinceJune 1, 2015AvailabilityAcademic Institutions and Nonprofits only -
MEK1 (S218D,S222D)-pcw107
Plasmid#64604Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertMAP2K1 (MAP2K1 Human)
UseLentiviralTagsExpressionMutationS218D, S222DPromoterPGKAvailable sinceJune 18, 2015AvailabilityAcademic Institutions and Nonprofits only -
Hras (G12V)-pcw107
Plasmid#64603Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertHRAS (HRAS Human)
UseLentiviralTagsExpressionMutationG12VPromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
p38 WT O/E (MAPK14)-pcw107-V5
Plasmid#64624Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertMAPK14 (transcript variant 2) (MAPK14 Human)
UseLentiviralTagsV5ExpressionMutationPromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
AR-V7-pcw107
Plasmid#64635Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertAR (transcript variant 1, splice isoform) (AR Human)
UseLentiviralTagsExpressionMutationsplice isoform*PromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
AR-V7-pcw107-V5
Plasmid#64636Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertAR (transcript variant 1, splice isoform) (AR Human)
UseLentiviralTagsV5ExpressionMutationsplice isoform *PromoterPGKAvailable sinceDec. 1, 2015AvailabilityAcademic Institutions and Nonprofits only -
IKKalpha (S176E,S180E)-pcw107-V5
Plasmid#64608Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertCHUK (CHUK Human)
UseLentiviralTagsV5ExpressionMutationS176E, S180EPromoterPGKAvailable sinceJune 18, 2015AvailabilityAcademic Institutions and Nonprofits only -
beta-catenin (S33A, S37A, T41A, S45A)-pcw107-V5
Plasmid#64613Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertCtnnb1 (Ctnnb1 Mouse)
UseLentiviralTagsV5ExpressionMutationS33A, S37A, T41A, S45APromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
beta-catenin (S33Y)-pcw107
Plasmid#64615Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertCTNNB1 (CTNNB1 Human)
UseLentiviralTagsExpressionMutationS33YPromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
beta-catenin (S33A, S37A, T41A, S45A)-pcw107
Plasmid#64612Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertCtnnb1 (Ctnnb1 Mouse)
UseLentiviralTagsExpressionMutationS33A, S37A, T41A, S45APromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
beta-catenin (S33Y)-pcw107-V5
Plasmid#64616Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertCTNNB1 (CTNNB1 Human)
UseLentiviralTagsV5ExpressionMutationS33YPromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
Notch1 intracellular domain-pcw107
Plasmid#64621Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertNOTCH1 (NOTCH1 Human)
UseLentiviralTagsExpressionMutationintracellular domain *PromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
myr-FLAG-AKT1-pcw107
Plasmid#64606Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertAKT1 (AKT1 Human)
UseLentiviralTagsFLAG and myristoylatedExpressionMutationPromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
pRSITEP-puro-shWRN2-C911
Plasmid#125786Purposea seed-matched control for pRSITEP-puro-shWRN2DepositorInsertshWRN2 (WRN Human)
UseRNAiTagsExpressionMutationPromoterAvailable sinceJune 27, 2019AvailabilityAcademic Institutions and Nonprofits only -
pRSITEP-puro-shWRN2
Plasmid#125785PurposeDOX-inducible expression of a short-hairpin RNA targeting human WRNDepositorInsertshWRN2 (WRN Human)
UseRNAiTagsExpressionMutationPromoterAvailable sinceAug. 21, 2019AvailabilityAcademic Institutions and Nonprofits only -
CHUK gRNA (BRDN0001149372)
Plasmid#77033Purpose3rd generation lentiviral gRNA plasmid targeting human CHUKDepositorInsertCHUK (CHUK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
Rgl2-CAAX-pcw107-V5
Plasmid#64641Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertRgl2 plus C-term KRAS (Kras Mouse)
UseLentiviralTagsV5ExpressionMutationC-term of KrasPromoterPGKAvailable sinceDec. 3, 2015AvailabilityAcademic Institutions and Nonprofits only -
shERK2a-mlpx-puro
Plasmid#65229Purposeencodes a shRNA against ERK2DepositorInsertshRNA against ERK2 (MAPK1 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceAug. 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
pKHH030_sgRB1#1
Plasmid#174144PurposeLentiviral vector expressing a sgRNA against the human RB1 geneDepositorInsertRB1 (RB1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceSept. 13, 2021AvailabilityAcademic Institutions and Nonprofits only