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Plasmid#76595Purpose3rd generation lentiviral gRNA plasmid targeting human CKMT2DepositorInsertCKMT2 (CKMT2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
CKMT2 gRNA (BRDN0001147460)
Plasmid#76596Purpose3rd generation lentiviral gRNA plasmid targeting human CKMT2DepositorInsertCKMT2 (CKMT2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
CKMT2 gRNA (BRDN0001148542)
Plasmid#76597Purpose3rd generation lentiviral gRNA plasmid targeting human CKMT2DepositorInsertCKMT2 (CKMT2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
rd-his
Plasmid#112911PurposeExpress the PEST domain-replaced 48 kDa form of human dematin with a cleavable N-terminal GST tag and non-cleavable C-terminal 6-his tagDepositorInsertdematin (DMTN Human)
UseTags6-his tag, Glutathione-S-Transferase, and preciss…ExpressionBacterialMutation89KSTSPPPSPEVWAD102 was replaced with 89KAAAGGGAG…PromoterT7Available sinceAug. 27, 2018AvailabilityAcademic Institutions and Nonprofits only -
pLV-Hyg-Snrnp40-CRISPR-resistant
Plasmid#134251PurposeLentivector encoding CRISPR-resistant Snrnp40DepositorInsertSnrp40 (Snrnp40 Mouse)
UseLentiviralTagsExpressionMammalianMutationmutated coding sequence “gataactatgcgacgttgaa” to…PromoterEF1aAvailable sinceMarch 19, 2020AvailabilityAcademic Institutions and Nonprofits only -
pX601-AAV-CMV::NLS-saCas9-NLS-3xHA-bGHpa;U6::BsaI-sgRNA-Grpr1
Plasmid#175176PurposeA single vector containing Cas9 from Staphylococcus aureus (SaCas9) and its sgRNA targeting GrprDepositorInsertsgRNA-Grpr
UseCRISPRTagsExpressionMutationPromoterAvailable sinceDec. 1, 2021AvailabilityAcademic Institutions and Nonprofits only -
MSCV-shCasp2-IRES-GFP
Plasmid#52061Purposestable knockdown of Caspase-2 in mammalian cellsDepositorInsertCaspase-2 shRNA (CASP2 Human)
UseRetroviralTagsIRES-EGFPExpressionMammalianMutationPromoterAvailable sinceMarch 13, 2014AvailabilityAcademic Institutions and Nonprofits only -
pX458-Ef1a-Cas9-H2B-mCherry (dual gRNA: Otx2 x2)
Plasmid#171102PurposeCRISPR/Cas9 expressing plasmid containing two gRNAs targeting mouse Otx2.DepositorInserthSpCas9 (Otx2 Mouse, S. pyogenes)
UseCRISPRTagsExpressionMutationPromoterEf1aAvailable sinceJune 28, 2021AvailabilityAcademic Institutions and Nonprofits only -
pPICZ:mTREK-1_cryst
Plasmid#133269PurposeP. pastoris expression vector. It will generate the mouse TREK-1 channel (21-322) fused to a C-terminal GFPDepositorInsertPotassium channel subfamily K member 2 (KCNK2, TREK-1) (Kcnk2 Mouse)
UseTagsSNS- 3C_cleavage_site-TAAA-GFPExpressionYeastMutationaa 21-322, K84R, Q85E, T86K, I88L, A89R, Q90A, A9…PromoterAvailable sinceApril 17, 2020AvailabilityAcademic Institutions and Nonprofits only -
RPS6KB1 gRNA (BRDN0001145729)
Plasmid#75612Purpose3rd generation lentiviral gRNA plasmid targeting human RPS6KB1DepositorInsertRPS6KB1 (RPS6KB1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
RPS6KB1 gRNA (BRDN0001145927)
Plasmid#75613Purpose3rd generation lentiviral gRNA plasmid targeting human RPS6KB1DepositorInsertRPS6KB1 (RPS6KB1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
BMX gRNA (BRDN0001146364)
Plasmid#75653Purpose3rd generation lentiviral gRNA plasmid targeting human BMXDepositorInsertBMX (BMX Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
FLAG-YAP2 (8SA)-pcw107
Plasmid#64637Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertYAP2 (transcript variant 3) (YAP1 Human)
UseLentiviralTagsFLAGExpressionMutation8SA*PromoterPGKAvailable sinceDec. 8, 2015AvailabilityAcademic Institutions and Nonprofits only -
CKS2 gRNA (BRDN0001147175)
Plasmid#77142Purpose3rd generation lentiviral gRNA plasmid targeting human CKS2DepositorInsertCKS2 (CKS2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
IRAK1 gRNA (BRDN0001145661)
Plasmid#76420Purpose3rd generation lentiviral gRNA plasmid targeting human IRAK1DepositorInsertIRAK1 (IRAK1 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DYRK2 gRNA (BRDN0001149060)
Plasmid#77538Purpose3rd generation lentiviral gRNA plasmid targeting human DYRK2DepositorInsertDYRK2 (DYRK2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
DYRK4 gRNA (BRDN0001149224)
Plasmid#75521Purpose3rd generation lentiviral gRNA plasmid targeting human DYRK4DepositorInsertDYRK4 (DYRK4 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
IRAK3 gRNA (BRDN0001146977)
Plasmid#77715Purpose3rd generation lentiviral gRNA plasmid targeting human IRAK3DepositorInsertIRAK3 (IRAK3 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
LIMK2 gRNA (BRDN0001147235)
Plasmid#75973Purpose3rd generation lentiviral gRNA plasmid targeting human LIMK2DepositorInsertLIMK2 (LIMK2 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only -
ALK gRNA (BRDN0001146138)
Plasmid#77393Purpose3rd generation lentiviral gRNA plasmid targeting human ALKDepositorInsertALK (ALK Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterhU6Available sinceJuly 6, 2016AvailabilityAcademic Institutions and Nonprofits only