168,736 results

1. pAAV-hSyn-miniDq-mCherry-P2A-HA-KORD

   Plasmid

   #204359

   Purpose

   AAV vector for coexpression of miniDq and KORD under the control of human synapsin promoter

   Depositor

   Masao Doi

   Article

   Miyake et al Cell Rep Methods. 2024 Oct 21;4(10):1008

   Insert

   miniDq-mCherry-P2A-HA-KORD
   

   Use

   AAV

   Tags

   HA (for KORD) and mCherry (for miniDq)

   Mutation

   For miniDq, the third intracellular loop (ICL3) o…

   Promoter

   hSyn

   Available Since

   Oct. 22, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCW57.1 Lysosomal-METRIQ

   Plasmid

   #135401

   Purpose

   Expresses lysosomal-METRIQ (DNAse II-sfGFP together with cytosolic RFP) to measure lysosomal activity

   Depositor

   Eisuke Itakura

   Article

   Ishii et al Sci Rep. 2019 Aug 12;9(1):11635. doi: 10

   Insert

   DNAse II alpha (DNASE2 Human)
   

   Use

   Lentiviral

   Tags

   T2A, mCherry, and sfGFP

   Expression

   Mammalian

   Mutation

   Single-nucleotide polymorphism C432T

   Available Since

   Feb. 26, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV-FLEX-ArchT-tdTomato (AAV5)

   Viral Prep

   #28305-AAV5

   Purpose

   Ready-to-use AAV5 particles produced from pAAV-FLEX-ArchT-tdTomato (#28305). In addition to the viral particles, you will also receive purified pAAV-FLEX-ArchT-tdTomato plasmid DNA. CAG-driven Cre-dependent ArchT-tdTomato expression for optogenetic neural inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Edward Boyden

   Article

   Han et al Front Syst Neurosci. 2011;5:18. Epub 201

   Promoter

   CAG

   Tags

   tdTomato (Cre-dependent)

   Available Since

   Feb. 7, 2018

   Availability

   Academic Institutions and Nonprofits only

4. pAAV-hSyn-DIO-hM4D(Gi)-mCherry (AAV1)

   Viral Prep

   #44362-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pAAV-hSyn-DIO-hM4D(Gi)-mCherry (#44362). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM4D(Gi)-mCherry plasmid DNA. hSyn-driven, Cre-dependent, hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV preparations are suitable purity for injection into animals.

   Depositor

   Bryan Roth

   Article

   Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d

   Promoter

   Syn

   Tags

   mCherry (Cre-dependent)

   Available Since

   May 26, 2020

   Availability

   Academic Institutions and Nonprofits only

5. pAAV-CAG-tdTomato (codon diversified)

   Plasmid

   #59462

   Purpose

   AAV-mediated expression of tdTomato (codon diversified) under the CAG promoter

   Depositor

   Edward Boyden

   Has Service

   AAV PHP.S, AAV PHP.eB, AAV Retrograde, AAV1, AAV2, AAV5, AAV8, and AAV9

   Insert

   tdTomato
   

   Use

   AAV

   Expression

   Mammalian

   Mutation

   codon diversified

   Promoter

   CAG

   Available Since

   Sept. 25, 2014

   Availability

   Academic Institutions and Nonprofits only

   

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6. pGP-AAV-syn-FLEX-jGCaMP8f-WPRE (AAV1)

   Viral Prep

   #162379-AAV1

   Purpose

   Ready-to-use AAV1 particles produced from pGP-AAV-syn-FLEX-jGCaMP8f-WPRE (#162379). In addition to the viral particles, you will also receive purified pGP-AAV-syn-FLEX-jGCaMP8f-WPRE plasmid DNA. Syn-driven, Cre-dependent expression of the ultrafast calcium sensor, GCaMP8f. These AAV preparations are suitable purity for injection into animals.

   Depositor

   GENIE Project

   Article

   Zhang et al Janelia Research Campus, Online Resource

   Promoter

   Syn

   Available Since

   May 18, 2021

   Availability

   Academic Institutions and Nonprofits only

7. pCHW101020

   Plasmid

   #222454

   Purpose

   Level 1, Position 2 containing 35S::CUP2-p65::NOS.

   Depositor

   Chih-Hang Wu

   Article

   Chiang et al bioRxiv 2024.03.23.586378

   Insert

   35S::CUP2-p65::NOS (CUP2 )
   

   Use

   Synthetic Biology

   Expression

   Plant

   Mutation

   no

   Available Since

   Nov. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. pH6HTC_PRMT1-Halo

   Plasmid

   #175334

   Purpose

   Production of HaloTag fusion protein

   Depositor

   Claudia Kutter

   Article

   Atanasoai et al bioRxiv 2021.11.08.467743

   Insert

   PRMT1 (PRMT1 Human)
   

   Use

   Cell free expression

   Tags

   HaloTag-6xHis

   Expression

   Bacterial

   Available Since

   Oct. 20, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. ABE8e

   Plasmid

   #138489

   Purpose

   A-to-G base editor

   Depositor

   David Liu

   Article

   Richter et al Nat Biotechnol. 2020 Jul;38(7):883-891.

   Insert

   ecTadA(8e)-nSpCas9
   

   Expression

   Mammalian

   Available Since

   March 16, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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10. pFast-hHus1

    Plasmid

    #222469

    Purpose

    Expresses hHus1 in insect cells

    Depositor

    Aziz Sancar

    Article

    Lindsey-Boltz et al Proc Natl Acad Sci U S A. 2001 Sep 25;98

    Insert

    hHus1 (HUS1 Human)
    

    Expression

    Insect

    Available Since

    Dec. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. VPS13D^mScarlet

    Plasmid

    #174110

    Purpose

    The insert is a codon optimized DNA sequence encoding VPS13D with an internal mScarlet protein.

    Depositor

    Pietro De Camilli

    Article

    Guillen-Samander et al J Cell Biol. 2021 May 3;220(5). pii: 212

    Insert

    Codon optimized VPS13D
    

    Tags

    mScarlet

    Expression

    Mammalian

    Mutation

    With an internal mScarlet tag in aminoacid positi…

    Promoter

    CMV

    Available Since

    Dec. 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. MoClo Yeast Toolkit

    Plasmid Kit

    #1000000061

    Purpose

    96 standardized parts used for bottom-up hierarchical assembly of single and multi-gene constructs for S. cerevisiae expression. Includes promoters, terminators, peptide tags, selection cassettes

    Depositor

    John Dueber

    Available Since

    June 16, 2015

    Availability

    Academic Institutions and Nonprofits only

13. pFast-Flag-hRad9

    Plasmid

    #222468

    Purpose

    Expresses hRad9 in insect cells

    Depositor

    Aziz Sancar

    Article

    Lindsey-Boltz et al Proc Natl Acad Sci U S A. 2001 Sep 25;98

    Insert

    hRad9 (RAD9A Human)
    

    Tags

    Flag epitope

    Expression

    Insect

    Available Since

    Dec. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pFast-hRad1

    Plasmid

    #222471

    Purpose

    Expresses hRad1 in insect cells

    Depositor

    Aziz Sancar

    Article

    Lindsey-Boltz et al Proc Natl Acad Sci U S A. 2001 Sep 25;98

    Insert

    hRad1 (RAD1 Human)
    

    Expression

    Insect

    Available Since

    Dec. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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15. pFast-His6-hRad17

    Plasmid

    #222465

    Purpose

    Expresses hRad17 in insect cells

    Depositor

    Aziz Sancar

    Article

    Lindsey-Boltz et al Proc Natl Acad Sci U S A. 2001 Sep 25;98

    Insert

    hRad17 (RAD17 Human)
    

    Tags

    His

    Expression

    Insect

    Available Since

    Dec. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pIVT_hifiDn29-dCas9-P2A-GFP

    Plasmid

    #247168

    Purpose

    In vitro transcription of human codon optimized fusion of hifiDn29-dCas9-P2A-GFP

    Depositor

    Patrick Hsu

    Article

    Fanton et al Nat Biotechnol. 2025 Nov 6. doi: 10.1038

    Insert

    hifiDn29-dCas9-P2A-GFP
    

    Use

    In vitro transcription

    Tags

    SV40 NLS

    Mutation

    M6I/E70G/A224P/G227V/Q332K/N341K/L393P/D503N/I98V…

    Promoter

    mutated T7

    Available Since

    Nov. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAVone-AAV9-CMV-eGFP

    Plasmid

    #230928

    Purpose

    pAAVone plasmid is used to package AAV-CMV-eGFP with an AAV9 serotype, utilizing the AAVone single-plasmid AAV production system.

    Depositor

    Qizhao Wang

    Article

    Yang et al Mol Ther Nucleic Acids. 2025 May 14;36(2

    Insert

    eGFP
    

    Use

    AAV

    Promoter

    CMV

    Available Since

    Jan. 16, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV2/5

    Plasmid

    #232922

    Purpose

    AAV packaging plasmid expressing AAV2 Rep protein and AAV5 capsid protein

    Depositor

    Melina Fan, Addgene Research Program

    Insert

    Rep2/Cap5
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Sept. 17, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

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19. AiP15072 - pAAV-AiE0680m-minBG-iCre(R297T)-BGHpA (Alias: CN5072)

    Plasmid

    #230402

    Purpose

    AiE0680m is an enhancer sequence, designed to drive AAV-mediated transgene expression in specific populations of brain cells

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Insert

    iCre(R297T)
    

    Use

    AAV

    Promoter

    minBG

    Available Since

    Feb. 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pAAV-CaMKIIa-hChR2(H134R)-EYFP (AAV5)

    Viral Prep

    #26969-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV-CaMKIIa-hChR2(H134R)-EYFP (#26969). In addition to the viral particles, you will also receive purified pAAV-CaMKIIa-hChR2(H134R)-EYFP plasmid DNA. CaMKIIa-driven, humanized channelrhodopsin H134R mutant fused to EYFP for optogenetic activation. These AAV preparations are suitable purity for injection into animals.

    Depositor

    Karl Deisseroth

    Article

    Lee et al Nature. 2010 Jun 10. 465(7299):788-92.

    Promoter

    CaMKII

    Tags

    EYFP

    Available Since

    March 7, 2018

    Availability

    Academic Institutions and Nonprofits only