Skip to main content
Addgene
Showing: 9141 - 9160 of 15052 results

  1. CIRTS-YTHDF2-Malat1

    Plasmid
    #216858
    Purpose
    CIRTS RNA targeting system for targeted knockdown of m6A-containing Malat1 at the synapse. CIRTS-YTHDF2-Calm3 and Malat1 gRNA is expressed under human Syn1 and U6 promoter, respectively.
    Depositor
    Timothy Bredy
    Article
    Madugalle et al J Neurosci. 2023 Oct 25;43(43):7084-7100
    Insert
    CIRTS-YTHDF2-Calm3-U6-Malat1 gRNA
    Use
    Lentiviral
    Tags
    GFP
    Expression
    Mammalian
    Mutation
    Promoter
    Syn1, U6
    Available since
    Aug. 29, 2024
    Availability
    Academic Institutions and Nonprofits only
    216858-plasmid-map-sequence-id-443348

    Enlarge

  2. AAV-KrasG13S/sgKras/Cre

    Plasmid
    #99859
    Purpose
    Expresses Cre-recombinase, a barcoded HDR template to introduce a G13S mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.
    Depositor
    Monte Winslow
    Article
    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:
    Insert
    Kras (Kras Mouse)
    Use
    AAV and Cre/Lox
    Tags
    Expression
    Mammalian
    Mutation
    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…
    Promoter
    Available since
    May 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    99859-plasmid-map-sequence-id-200267

    Enlarge

  3. AAV-KrasG13A/sgKras/Cre

    Plasmid
    #99855
    Purpose
    Expresses Cre-recombinase, a barcoded HDR template to introduce a G13A mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.
    Depositor
    Monte Winslow
    Article
    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:
    Insert
    Kras (Kras Mouse)
    Use
    AAV and Cre/Lox
    Tags
    Expression
    Mammalian
    Mutation
    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…
    Promoter
    Available since
    May 10, 2018
    Availability
    Academic Institutions and Nonprofits only
    99855-plasmid-map-sequence-id-200262

    Enlarge

  4. AAV-KrasG13R/sgKras/Cre

    Plasmid
    #99858
    Purpose
    Expresses Cre-recombinase, a barcoded HDR template to introduce a G13R mutation into the endogenous Kras locus, and a Kras-targeting sgRNA to enhance HDR.
    Depositor
    Monte Winslow
    Article
    Winters et al Nat Commun. 2017 Dec 12;8(1):2053. doi:
    Insert
    Kras (Kras Mouse)
    Use
    AAV and Cre/Lox
    Tags
    Expression
    Mammalian
    Mutation
    AvrII site (CAAAGG>CCTAGG), PAM/sgRNA mutation…
    Promoter
    Available since
    Dec. 13, 2017
    Availability
    Academic Institutions and Nonprofits only
    99858-plasmid-map-sequence-id-193748

    Enlarge

  5. pCX459

    Plasmid
    #229214
    Purpose
    CRISPR array plasmid for MAP1B (Spacers 1-24)
    Depositor
    Jennifer Doudna
    Article
    Xia et al Nat Biotechnol (2025)
    Insert
    CRISPR array plasmid for MAP1B (Spacers 1-24)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    Feb. 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    229214-plasmid-map-sequence-id-457231

    Enlarge

  6. pCX137

    Plasmid
    #229212
    Purpose
    CRISPR array plasmid for NOTCH2 (Spacers 1-24)
    Depositor
    Jennifer Doudna
    Article
    Xia et al Nat Biotechnol (2025)
    Insert
    CRISPR array plasmid for NOTCH2 (Spacers 1-24)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    Feb. 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    229212-plasmid-map-sequence-id-457234

    Enlarge

  7. pCX138

    Plasmid
    #229213
    Purpose
    CRISPR array plasmid for NOTCH2 (Spacers 25-48)
    Depositor
    Jennifer Doudna
    Article
    Xia et al Nat Biotechnol (2025)
    Insert
    CRISPR array plasmid for NOTCH2 (Spacers 25-48)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    Feb. 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    229213-plasmid-map-sequence-id-457233

    Enlarge

  8. pCX460

    Plasmid
    #229215
    Purpose
    CRISPR array plasmid for MAP1B (Spacers 25-48)
    Depositor
    Jennifer Doudna
    Article
    Xia et al Nat Biotechnol (2025)
    Insert
    CRISPR array plasmid for MAP1B (Spacers 25-48)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    Feb. 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    229215-plasmid-map-sequence-id-457230

    Enlarge

  11. pLKO-Tet-On-ARNTL-shRNA1

    Plasmid
    #166913
    Purpose
    Lentivirus for inducible knockdown of human ARNTL(BMAL1)
    Depositor
    Roland Friedel
    Insert
    ARNTL shRNA (BMAL1 Human)
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    March 14, 2024
    Availability
    Academic Institutions and Nonprofits only
    166913-plasmid-map-sequence-id-425230

    Enlarge

  12. pLKO-Tet-On-ARNTL-shRNA2

    Plasmid
    #166914
    Purpose
    Lentivirus for inducible knockdown of human ARNTL(BMAL1)
    Depositor
    Roland Friedel
    Insert
    ARNTL shRNA (BMAL1 Human)
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    March 14, 2024
    Availability
    Academic Institutions and Nonprofits only
    166914-plasmid-map-sequence-id-331230

    Enlarge

  13. pLKO-Tet-On-ARNTL-shRNA3

    Plasmid
    #166915
    Purpose
    Lentivirus for inducible knockdown of human ARNTL(BMAL1)
    Depositor
    Roland Friedel
    Insert
    ARNTL shRNA (BMAL1 Human)
    Use
    Lentiviral
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    March 14, 2024
    Availability
    Academic Institutions and Nonprofits only
    166915-plasmid-map-sequence-id-331234

    Enlarge

  16. pLKO-Tet-puro-hRAF1-shRNA-1

    Plasmid
    #185371
    Purpose
    For tetracycline-inducible mammalian expression of shRNA: CATGAGTATTTAGAGGAAGTA that targets human RAF1
    Depositor
    Ayaz Najafov
    Insert
    RAF1 (RAF1 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    WT
    Promoter
    Available since
    June 6, 2022
    Availability
    Academic Institutions and Nonprofits only
    185371-plasmid-map-sequence-id-363455

    Enlarge

  19. pLKO.1-blast shLuc

    Plasmid
    #110409
    Purpose
    shLuc (Target TTACGCTGAGTACTTCGA), silence LUC gene, blasticidin selection.
    Depositor
    Sandra Martha Gomes Dias
    Insert
    Luciferase
    Use
    Lentiviral and RNAi
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    U6 (RNA PolIII)
    Available since
    Nov. 5, 2018
    Availability
    Academic Institutions and Nonprofits only
    110409-plasmid-map-sequence-id-254625

    Enlarge

Showing: 9141 - 9160 of 15052 results