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Showing: 701 - 720 of 736 results

  1. GCN5 FL-dCas9-p300 core

    Plasmid
    #179554
    Purpose
    encodes S. pyogenes dCas9 with n-terminal fusion of full length human GCN5 and c-terminal fusion of human p300 core (aa 1048-1664) driven by EF-1alpha promoter
    Depositor
    Isaac Hilton
    Article
    Wang et al Nucleic Acids Res. 2022 Aug 12;50(14):78
    Insert
    S. pyogenes dCas9 with n-terminal fusion of full length human GCN5 and c-terminal fusion of human p300 core (aa 1048-1664) (EP300, KAT2A Human)
    Use
    Lentiviral
    Tags
    Flag Tag
    Expression
    Mammalian
    Mutation
    D10A; H840A in S.pyogenes Cas9
    Promoter
    EF-1alpha
    Available since
    Feb. 17, 2022
    Availability
    Academic Institutions and Nonprofits only
    179554-plasmid-map-sequence-id-354754

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  3. GCN5 core-dCas9-p300 core

    Plasmid
    #179553
    Purpose
    encodes S. pyogenes dCas9 with n-terminal fusion of human GCN5 core (aa 473-676) and c-terminal fusion of human p300 core (aa 1048-1664) driven by EF-1alpha promoter
    Depositor
    Isaac Hilton
    Article
    Wang et al Nucleic Acids Res. 2022 Aug 12;50(14):78
    Insert
    S. pyogenes dCas9 with n-terminal fusion of human GCN5 core (aa 473-676) and c-terminal fusion of human p300 core (aa 1048-1664) (EP300, KAT2A Human)
    Use
    Lentiviral
    Tags
    Flag Tag
    Expression
    Mammalian
    Mutation
    D10A; H840A in S.pyogenes Cas9
    Promoter
    EF-1alpha
    Available since
    Feb. 18, 2022
    Availability
    Academic Institutions and Nonprofits only
    179553-plasmid-map-sequence-id-354783

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  4. Mouse SLC KO Library

    Pooled Library
    #141436
    Purpose
    Expresses gRNAs for knockout of the mouse Solute Carrier family
    Depositor
    Giulio Superti-Furga
    Expression
    Mammalian
    Species
    Mus musculus
    Use
    CRISPR and Lentiviral
    Available since
    May 18, 2020
    Availability
    Academic Institutions and Nonprofits only

  7. Human ubiquitination-related proteins CRISPR KO library

    Pooled Library
    #174592
    Purpose
    CRISPR Cas9 KO library targets 660 ubiquitination-related proteins, including all major E1, E2, E3 and deubiquitinating enzymes, as well as other ubiquitination-related proteins.
    Depositor
    Juan Bonifacino
    Article
    Jia et al Elife. 2019 Nov 6;8. pii: 50034. doi: 10
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Nov. 30, 2021
    Availability
    Academic Institutions and Nonprofits only

  11. Pan-Druggable Cancer Library

    Pooled Library
    #182133
    Purpose
    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.
    Depositor
    Prashant Mali
    Article
    Hu et al Biomaterials. 2022 Jan;280:121276. doi:
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available since
    Aug. 26, 2022
    Availability
    Academic Institutions and Nonprofits only
Showing: 701 - 720 of 736 results