LentiCRISPRv2 variant with modified sgRNA scaffold from Chen et al. 2013 Cell.

Mammalian expression and labeling mitofusin 1

Ready-to-use AAV Retrograde particles produced from pAAV.Syn.NES-jRGECO1a.WPRE.SV40 (#100854). In addition to the viral particles, you will also receive purified pAAV.Syn.NES-jRGECO1a.WPRE.SV40 plasmid DNA. Synapsin-driven GECO1a calcium sensor. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.

pCMV-bpSV40 NLS-TadA8e(2-76)-2xFRB-BGHpA

pCMV-SV40_NLS-2xFKBP3-TadA-8e(77-167)-SpCas9(D10A)-SV40_NLS-BGHpA

Mammalian Expression, Lentiviral vector expressing GFP for two-colour competitive growth assay. Clone guide oligos into BsmBI site.

Ready-to-use AAV PHP.eB particles produced from pAAV_BiLAMP5e3_dTomato_nlsdTomato_nlsdTomato (#213914). In addition to the viral particles, you will also receive purified pAAV_BiLAMP5e3_dTomato_nlsdTomato_nlsdTomato plasmid DNA. Tricistronic expression of dTomato and nuclear-targeted dTomato under the control of the Lamp5 interneuron-targeting enhancer E3. These AAV were produced with the PHPeB serotype, which permits efficient transduction of the central nervous system. These AAV preparations are suitable purity for injection into animals.

expresses ABE8.20-m in mammalian cells

Bacterial expression of Pfu DNA polymerase

Bacterial expression of Pfu DNA polymerase

Vector optimized for use in screening assays, as well as for efficient production of baculovirus and robust expression of the target protein

Ready-to-use AAV9 particles produced from pAAV-Ef1a-DIO eNpHR 3.0-EYFP (#26966). In addition to the viral particles, you will also receive purified pAAV-Ef1a-DIO eNpHR 3.0-EYFP plasmid DNA. EF1a-driven, cre-dependent eNpHR 3.0-EYFP for optogenetic inhibition. These AAV preparations are suitable purity for injection into animals.

Constitutive lentiviral expression of human FURIN.

AAV zinc finger donor vector for genomic targeting

AAV zinc finger donor vector for genomic targeting

visualization of mitochondria