Addgene

We narrowed to 6,681 results for: aav

Showing: 5041 - 5060 of 6681 results

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Circular 200,100 (mIDUA)

Plasmid

#170123

Purpose

AAV vector carrying 2 copies of a guide RNA targeting the mouse IDUA mRNA, expressed from human and mouse U6 promoters

Depositor

Prashant Mali

Article

Katrekar et al Nat Biotechnol. 2022 Feb 10. pii: 10.103

Insert

Circular 200,100 guide RNA (Idua Mouse)

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

Human U6 and mouse U6

Available since

Feb. 11, 2022

Availability

Academic Institutions and Nonprofits only

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pEMS1983

Plasmid

#49114

Purpose

AAV plasmid with PITX3 (Ple253) promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple253-iCre

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

PITX3

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS1989

Plasmid

#49120

Purpose

AAV plasmid with CAGGS promoter driving expression of iCre. Contains WPRE.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-CAGGS-iCre-WPRE

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

CAGGS

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS1984

Plasmid

#49115

Purpose

AAV plasmid with PITX3 (Ple253) promoter driving expression of iCre. Contains WPRE.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple253-iCre-WPRE

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

PITX3

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2058

Plasmid

#49136

Purpose

AAV plasmid with CAGGS promoter driving expression of EmGFP. Contains WPRE.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-CAGGS-emGFP-WPRE

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

CAGGS

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS1978

Plasmid

#49110

Purpose

AAV plasmid with C8ORF46 (Ple251) promoter driving expression of iCre. Contains WPRE.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple251-icre-WPRE

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

C8ORF46

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2026

Plasmid

#49133

Purpose

AAV plasmid with TNNT1-B (Ple301) promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple301-iCre

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

TNNT1-B

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pDF0428 huDisCas7-11-R1045-GGGS-R1122-U6-pro-Gluc

Plasmid

#186985

Purpose

AAV transgene plasmid for Cas7-11-R1045-GGGS-R1122, with U6 promoter-driven expression of Gluc crRNA guide

Depositor

Jonathan Gootenberg, Omar Abudayyeh

Article

Kato et al Cell. 2022 May 25. pii: S0092-8674(22)00

Insert

cas7-11-r1045-gggs-r1122, Gluc crRNA guide

Use

AAV

Tags

Expression

Mutation

r1045-gggs-r1122 deletion

Promoter

Available since

Sept. 6, 2022

Availability

Academic Institutions and Nonprofits only

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pEMS2023

Plasmid

#49130

Purpose

AAV plasmid with hs1218 promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-hs1218-iCre

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

hs1218

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2024

Plasmid

#49131

Purpose

AAV plasmid with hs671 promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-hs671-iCre

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

hs671

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2025

Plasmid

#49132

Purpose

AAV plasmid with NOV (Ple303) promoter driving expression of iCre.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-Ple303-iCre

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

NOV

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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pEMS2050

Plasmid

#49135

Purpose

AAV plasmid with CAGGS promoter driving expression of EmGFP.

Depositor

Elizabeth Simpson

Article

Simpson et al Hum Gene Ther. 2018 Jul 31. doi: 10.1089

Insert

ssAAV-CAGGS-emGFP

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

CAGGS

Available since

May 10, 2016

Availability

Industry, Academic Institutions, and Nonprofits

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hSyn-FAS-DO-ReaChR-mCitrine-WPRE

Plasmid

#64035

Purpose

Expresses ReaChR under hSyn promoter. FAS-DO turns off expression in Cre-positive cells. FAS is compatible with other traditional Flex/DIO constructs

Depositor

Karel Svoboda

Insert

hSyn-FAS-DO-ReaChR-mCitrine-WPRE

Use

AAV

Tags

ReaChR tagged with mCitrine

Expression

Mammalian

Mutation

Promoter

hSyn

Available since

May 27, 2015

Availability

Academic Institutions and Nonprofits only
GFP pA_EB_CAGW

Plasmid

#92154

Purpose

AAV construct encoding GFP control

Depositor

Weifeng Xu

Article

Han et al Cell Rep. 2017 Jan 24;18(4):892-904. doi

Insert

EGFP

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

CAGW

Available since

April 20, 2018

Availability

Academic Institutions and Nonprofits only

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pAM/CBA-eGFP-miRaSyn(mouse)x3-WPRE-bGHpA

Plasmid

#194248

Purpose

Expresses 3 miRNAs targeting mouse alpha-Synuclein

Depositor

Michael J Fox Foundation MJFF

Insert

miRaSynuclein(mouse) (Snca Mouse)

Use

AAV and RNAi

Tags

Expression

Mutation

Promoter

CAG

Available since

Jan. 24, 2023

Availability

Academic Institutions and Nonprofits only

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EF1a-DIO-PSAML-141F,Y115F- GlyR-2A-FusionRed

Plasmid

#226590

Purpose

Pharmacologically Selective Actuator Module, chimeric ligand-gated ion channels that can be used to manipulate electrophysiological activity.

Depositor

D. James Surmeier

Insert

EF1a-DIO-PSAML-141F,Y115F- GlyR-2A-FusionRed

Use

AAV

Tags

Fusion Red

Expression

Mammalian

Mutation

Promoter

Available since

Nov. 1, 2024

Availability

Academic Institutions and Nonprofits only

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pGEARBOCS-v0

Plasmid

#196495

Purpose

CRISPR tool to target astrocytes

Depositor

Cagla Eroglu

Article

Bindu et al bioRxiv. 2023 Jan 19:2023.01.17.524433.

Type

Empty backbone

Use

AAV and CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Aug. 23, 2024

Availability

Academic Institutions and Nonprofits only

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pgfaABC1D-mCherry-CAAX

Plasmid

#196488

Purpose

To over express mCherry-CAAX under gfaABC1D promoter in astrocytes

Depositor

Cagla Eroglu

Article

Bindu et al bioRxiv. 2023 Jan 19:2023.01.17.524433.

Insert

mCherry-CAAX

Use

AAV

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Aug. 23, 2024

Availability

Academic Institutions and Nonprofits only

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pGEARBOCS-v0-Gfap-KO

Plasmid

#196489

Purpose

To KO Gfap in mouse astrocytes

Depositor

Cagla Eroglu

Article

Bindu et al bioRxiv. 2023 Jan 19:2023.01.17.524433.

Insert

gRNA

Use

AAV and CRISPR

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Aug. 23, 2024

Availability

Academic Institutions and Nonprofits only

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v3em-Cterm-PE6d-dualU6-Dnmt1-PE3-loxP

Plasmid

#207863

Purpose

AAV genome encoding C-terminal PE6d and U6 expression cassettes for Dnmt1 PE3 pegRNA and ngRNA

Depositor

David Liu

Article

Doman et al Cell. 2023 Aug 31;186(18):3983-4002.e26.

Insert

NpuC-Cterm-PE6d-dualU6-Dnmt1-PE3-loxP

Use

AAV

Tags

Expression

Mutation

See Manuscript

Promoter

Cbh

Available since

Sept. 27, 2023

Availability

Academic Institutions and Nonprofits only

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