Addgene

We narrowed to 23,533 results for: SPR

Showing: 361 - 380 of 23533 results

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LentiCRISPR-sgC1orf27-2

Plasmid

#86131

Purpose

Lentiviral vector expressing Cas9 and an sgRNA targeting C1orf27

Depositor

David Sabatini

Article

Wang et al Cell. 2017 Feb 1. pii: S0092-8674(17)300

Insert

sgRNA 2 targeting C1orf27 (C1orf27 )

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6

Available since

Feb. 22, 2017

Availability

Academic Institutions and Nonprofits only

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LentiCRISPRv2-sgSORCS2-G2

Plasmid

#118416

Purpose

CRISPR knockout, expresses Cas9, and sgRNA targeting Human SORCS2

Depositor

Mark Denham

Article

Hojland Knudsen et al Front Cell Dev Biol. 2018 May 15;6:54. d

Insert

gRNA SORCS2 Human (SORCS2 Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mutation

Promoter

Available since

Nov. 13, 2018

Availability

Academic Institutions and Nonprofits only

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4CE1A cSpry1

Plasmid

#22095

Depositor

Gail Martin

Insert

Sprouty 1 (SPRY1 Chicken)

Use

Bacterial

Tags

Expression

Mutation

Promoter

Available since

Sept. 17, 2009

Availability

Academic Institutions and Nonprofits only
pLentiCRISPR sgFTCD_1

Plasmid

#102312

Purpose

genetic depletion of FTCD

Depositor

David Sabatini

Article

Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

Insert

sgFTCD_1 (FTCD Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPR sgFTCD_2

Plasmid

#102313

Purpose

genetic depletion of FTCD

Depositor

David Sabatini

Article

Kanarek et al Nature. 2018 Jul 11. pii: 10.1038/s41586

Insert

sgFTCD_2 (FTCD Human)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

U6

Available since

July 13, 2018

Availability

Academic Institutions and Nonprofits only

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3CB1/cSprouty2

Plasmid

#22096

Depositor

Gail Martin

Article

Minowada et al Development. 1999 Oct . 126(20):4465-75.

Insert

Sprouty 2 (SPRY2 Chicken)

Use

Bacterial

Tags

Expression

Mutation

Promoter

Available since

Sept. 17, 2009

Availability

Academic Institutions and Nonprofits only
CRISPR plasmid

Plasmid

#236553

Purpose

Encodes Cas9 and two guideRNAs, one to cut the genome downstream of HSPA5 (BiP/GRP78) and one to linearize the DONOR plasmid.

Depositor

Pablo Rivera-Fuentes

Insert

Cas9

Use

Tags

Expression

Mammalian

Mutation

Promoter

Available since

April 23, 2025

Availability

Academic Institutions and Nonprofits only

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CRISPRoff-mScarletI

Plasmid

#217783

Purpose

Expresses CRISPRoff-mScarletI (DNMT3A-DNMT3L-XTEN80-dCas9-HA-2xNLS-mScarletI-KRAB) downstream of the CAG promoter for gene epigenetic silencing

Depositor

Adriano Aguzzi

Article

Yin et al Nat Biomed Eng. 2024 Dec 4. doi: 10.1038

Insert

CRISPRoff-mScarletI (DNMT3A-DNMT3L-dCas9-mScarletI-KRAB)

Use

Tags

2xNLS, DNMT3A-DNMT3L, HA, KRAB, and mScarletI

Expression

Mammalian

Mutation

Promoter

CAG

Available since

April 14, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgPnpt1-2#

Plasmid

#234770

Purpose

knockout Pnpt1

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Pnpt1 (Pnpt1 )

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 28, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgPnpt1-1#

Plasmid

#234769

Purpose

knockout Pnpt1

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Pnpt1 (Pnpt1 )

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 28, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgCrls1-1#

Plasmid

#234765

Purpose

knockout Crls1

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Crls1 (Crls1 Mouse)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPRv2-sgCTL

Plasmid

#234771

Purpose

Non Targeting Control

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Non Targeting Control sgRNA

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgCrls1-2#

Plasmid

#234766

Purpose

knockout Crls

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Crls1 (Crls1 Mouse)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgPlscr3-2#

Plasmid

#234772

Purpose

knockout Plscr3

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Plscr3 (Plscr3 Mouse)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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lentiCRISPR v2-sgPlscr3-1#

Plasmid

#234767

Purpose

knockout Plscr3

Depositor

Judy Lieberman

Article

Miao et al Immunity. 2023 Nov 14;56(11):2523-2541.e

Insert

Plscr3 (Plscr3 Mouse)

Use

Lentiviral

Tags

Expression

Mutation

Promoter

Available since

March 27, 2025

Availability

Academic Institutions and Nonprofits only

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LentiCRISPRv2-ACTB-C4

Plasmid

#229849

Purpose

Expresses wild-type Cas9 and gRNA for ACTB gene. The target sequence is changed from ACTB-C1 to improve the cut efficiency.

Depositor

Natsuko Chiba

Insert

guide RNA for ACTB gene

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

Available since

Feb. 20, 2025

Availability

Academic Institutions and Nonprofits only

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ABE8e-SpRY

Plasmid

#226858

Purpose

Expresses ABE8e-SpRY base editor in mammalian cells with eGFP marker

Depositor

Alexis Komor

Article

Osgood et al Methods in Enzymology, February 5, 2025

Insert

ABE8e-SpRY

Use

Tags

Expression

Mammalian

Mutation

Promoter

CMV

Available since

Feb. 10, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRpuro-sgROSA26

Plasmid

#231562

Purpose

pLentiCRISPR expression vector for Cas9 and gRNA targeting human ROSA26 locus (Puromycin selection marker)

Depositor

Rizwan Haq

Article

Schiantarelli et al Cancer Cell. 2025 Feb 10;43(2):308-316.e

Insert

sgROSA26

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6, EF-1a

Available since

Feb. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRpuro-sgSEC24C #2

Plasmid

#231564

Purpose

pLentiCRISPR expression vector for Cas9 and gRNA targeting human SEC24C (#2) (Puromycin selection marker)

Depositor

Rizwan Haq

Article

Schiantarelli et al Cancer Cell. 2025 Feb 10;43(2):308-316.e

Insert

sgSEC24C #2 (SEC24C Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6, EF-1a

Available since

Feb. 3, 2025

Availability

Academic Institutions and Nonprofits only

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pLentiCRISPRpuro-sgSEC24C #1

Plasmid

#231563

Purpose

pLentiCRISPR expression vector for Cas9 and gRNA targeting human SEC24C (#1) (Puromycin selection marker)

Depositor

Rizwan Haq

Article

Schiantarelli et al Cancer Cell. 2025 Feb 10;43(2):308-316.e

Insert

sgSEC24C #1 (SEC24C Human)

Use

CRISPR and Lentiviral

Tags

Expression

Mammalian

Mutation

Promoter

U6, EF-1a

Available since

Feb. 3, 2025

Availability

Academic Institutions and Nonprofits only

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