CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.
Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E, Boix C, Perrouault L, Tesson L, Geny S, De Cian A, Itier JM, Anegon I, Lopez B, Giovannangeli C, Concordet JP
Nat Commun. 2018 Mar 19;9(1):1133. doi: 10.1038/s41467-018-03475-7. PubMed
Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E, Boix C, Perrouault L, Tesson L, Geny S, De Cian A, Itier JM, Anegon I, Lopez B, Giovannangeli C, Concordet JP
Nat Commun. 2018 Mar 19;9(1):1133. doi: 10.1038/s41467-018-03475-7. PubMed
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 109400 | pCas9-HE | Expresses Cas9 fusion to HE (HDR-enhancer) domain of human CtIP protein |
| 109401 | pCas9-Geminin | Expresses Cas9 fusion to Geminin degron domain |
| 109402 | pCas9-HE-Geminin | Expresses Cas9 fusion to HE (HDR-enhancer) domain of human CtIP protein and Geminin degron |
| 109403 | pCas9-CtIP | Expresses Cas9 fusion to human CtIP protein |