Somatic genome editing with CRISPR/Cas9 generates and corrects a metabolic disease.
Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR
Sci Rep. 2017 Mar 16;7:44624. doi: 10.1038/srep44624. PubMed Article
Jarrett KE, Lee CM, Yeh YH, Hsu RH, Gupta R, Zhang M, Rodriguez PJ, Lee CS, Gillard BK, Bissig KD, Pownall HJ, Martin JF, Bao G, Lagor WR
Sci Rep. 2017 Mar 16;7:44624. doi: 10.1038/srep44624. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 89060 | 1179_pAAV-U6-BbsI-gRNA-CB-EmGFP | AAV-gRNA cloning vector with GFP reporter |
| 89061 | 1183_pAAV-U6-Ex14-gRNAd-CB-EmGFP | AAV-gRNA targeting the murine Ldlr gene |
| 89062 | 1184_pAAV-U6-ApoB-gRNA2-CB-EmGFP | AAV-gRNA targeting the murine Apob gene |