Systematic identification of signaling pathways with potential to confer anticancer drug resistance.
Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, Anderson GR, Winter PS, Wang T, Alley HM, Kwong LN, Cooper ZA, Tetzlaff M, Chen PL, Rathmell JC, Flaherty KT, Wargo JA, McDonnell DP, Sabatini DM, Wood KC
Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. PubMed Article
Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, Anderson GR, Winter PS, Wang T, Alley HM, Kwong LN, Cooper ZA, Tetzlaff M, Chen PL, Rathmell JC, Flaherty KT, Wargo JA, McDonnell DP, Sabatini DM, Wood KC
Sci Signal. 2014 Dec 23;7(357):ra121. doi: 10.1126/scisignal.aaa1877. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 62511 | pcw107 | Gateway Expression Vector |
| 64602 | Kras (G12V)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64603 | Hras (G12V)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64604 | MEK1 (S218D,S222D)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64605 | myr-FLAG-PIK3CA-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64606 | myr-FLAG-AKT1-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64607 | FLAG-Rheb (Q64L)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64608 | IKKalpha (S176E,S180E)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64609 | FLAG-IKKbeta (S177E,S181E)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64610 | JAK2 (V617F)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64611 | Stat3 (A662C,N664C,V667L)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64612 | beta-catenin (S33A, S37A, T41A, S45A)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64613 | beta-catenin (S33A, S37A, T41A, S45A)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64614 | GSK3beta (K85A)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64615 | beta-catenin (S33Y)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64616 | beta-catenin (S33Y)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64617 | JNK2 WT O/E (MAPK9)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64618 | FLAG-Mkk7-JNK2 fusion-pcw107 | Mkk7-JNK2 fusion - barcoded activating construct of JNK pathway |
| 64619 | MEK5 DD(S311D,T315D)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64620 | myr-FLAG-MEK5-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64621 | Notch1 intracellular domain-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64622 | Notch1 intracellular domain-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64623 | Notch3 intracellular domain-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64624 | p38 WT O/E (MAPK14)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64625 | FLAG-MKK6 (S207E,T211E)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64626 | Gli2 truncation-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64627 | SmoM2 (W535L)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64628 | SmoM2 (W535L)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64629 | TGFbetaR1 (T204D)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64630 | BCL2-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64631 | BCL-XL-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64632 | Caspase-8 (C360A)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64633 | Caspase-3 (C163A)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64634 | ERalpha (Y537S mutant)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64635 | AR-V7-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64636 | AR-V7-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64637 | FLAG-YAP2 (8SA)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64638 | p53 (dominant negative R175H mutant)-pcw107-V5 | 3rd generation lentiviral transfer plasmid. When used to produce lentivirus, express physiological levels of insert |
| 64639 | HRas (G12V, E37G)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64640 | HRas (G12V, E37G)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64641 | Rgl2-CAAX-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64642 | RalA (G23V)(mature peptide)-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64643 | RalA (G23V)(mature peptide)-pcw107-V5 | when used to produce lentivirus, express physiological levels of insert |
| 64644 | RalA (G23V)( full )-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64645 | RalA (G23V)( full )-pcw107-V5 | (control) when used to produce lentivirus, express physiological levels of insert |
| 64646 | HcRed-pcw107 | when used to produce lentivirus, express physiological levels of insert |
| 64647 | HcRed-pcw107-V5 | (control) when used to produce lentivirus, express physiological levels of insert |
| 64648 | Luciferase-pcw107 | (control) when used to produce lentivirus, express physiological levels of insert |
| 64649 | Luciferase-pcw107-V5 | (control) when used to produce lentivirus, express physiological levels of insert |
| 64650 | MEK1-pcw107-V5 | (control) when used to produce lentivirus, express physiological levels of insert |