Scalable signaling mediated by T cell antigen receptor-CD3 ITAMs ensures effective negative selection and prevents autoimmunity.
Holst J, Wang H, Eder KD, Workman CJ, Boyd KL, Baquet Z, Singh H, Forbes K, Chruscinski A, Smeyne R, van Oers NS, Utz PJ, Vignali DA
Nat Immunol. 2008 Jun;9(6):658-66. doi: 10.1038/ni.1611. Epub 2008 May 11.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
52092 | Murine CD3 WTdelta-F2A-gamma-T2A-epsilon-P2A-zeta pMIG II | Retroviral expression of all four WT CD3 subunits, co-expressed with EGFP |
52093 | Murine CD3 WTdelta-F2A-gamma-T2A-epsilon-P2A-zeta pMIA II | Retroviral expression of all four WT CD3 subunits, co-expressed with mAmetrine |