A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo.
Yoo SH, Ko CH, Lowrey PL, Buhr ED, Song EJ, Chang S, Yoo OJ, Yamazaki S, Lee C, Takahashi JS
Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2608-13. Epub 2005 Feb 7.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 48741 | pGL1 | Expression of luciferase driven by truncated mPer2 promoter region (bases -1128 to -141 with respect to transcription start site at +1) |
| 48742 | pGL2 | Expression of luciferase driven by truncated mPer2 promoter region (bases -1128 to +386 with respect to transcription start site at +1) |
| 48743 | pGL3 | Expression of luciferase driven by truncated mPer2 promoter region (bases -1128 to +1060 with respect to transcription start site at +1) |
| 48744 | pGL4 | Expression of luciferase driven by truncated mPer2 promoter region (bases -1128 to +1536 with respect to transcription start site at +1) |
| 48745 | pGL5 | Expression of luciferase driven by truncated mPer2 promoter region (bases -1128 to +2064 with respect to transcription start site at +1) |
| 48746 | pGL6 | Expression of luciferase driven by mPer2 promoter region (bases -1128 to +2129 with respect to transcription start site at +1) |
| 48747 | pGL3 basic E2 | Expression of luciferase driven by mPer2 promoter fragment containing E-box2 (bases -112 to +98 with respect to transcription start site at +1) |
| 48748 | pGL3 basic Mut E2 | Expression of luciferase driven by mPer2 promoter fragment containing mutated E-box2 (bases -112 to +98 with respect to transcription start site at +1) |
| 48749 | pGL3 Pro E2 | Expression of luciferase driven by mPer2 promoter fragment containing E-box2 (bases -112 to +98 with respect to transcription start site at +1) and SV40 promoter (backbone) |
| 48750 | pGL3 Pro Mut E2 | Expression of luciferase driven by mPer2 promoter fragment containing mutated E-box2 (bases -112 to +98 with respect to transcription start site at +1) and SV40 promoter (backbone) |