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A high-light sensitivity optical neural silencer: development and application to optogenetic control of non-human primate cortex.

Han X, Chow BY, Zhou H, Klapoetke NC, Chuong A, Rajimehr R, Yang A, Baratta MV, Winkle J, Desimone R, Boyden ES
Front Syst Neurosci. 2011;5:18. Epub 2011 Apr 13. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
28305pAAV-FLEX-ArchT-tdTomatoCre-dependent viral expression of ArchT-tdTomato for neuronal inhibition
28307pAAV-FLEX-ArchT-GFPCre-dependent viral expression of ArchT-GFP for neuronal inhibition
29777pAAV-CAG-ArchT-GFPAAV-mediated expression of ArchT-GFP for neuronal inhibition
29778pAAV-CAG-ArchT-tdTomatoAAV-mediated expression of ArchT-tdTomato for neuronal inhibition
31177FCK-ArchT-GFPLentiviral expression of ArchT-GFP for neuronal inhibition
37807pAAV-CamKII-ArchT-GFPViral expression of ArchT-GFP for optogenetic inhibition
58851pAAV-EF1a-FLEX-ArchT-GFPAAV-mediated expression of ArchT-GFP under the EF1a promoter, in floxed/reversed (Cre-dependent) manner
63141pAAV-Syn-ArchT-GFPAAV-mediated expression of ArchT-GFP under the Syn promoter. Using hGHpA signal.
99039pAAV-CamKII-ArchT-GFP (PV2527)AAV-mediated expression of ArchT under the CamKII promoter
123607pAAV-Syn-FLEX-rc [ArchT-tdTomato]AAV mediated expression of ArchT-tdTomato under the Syn promoter, in floxed/reversed (Cre-dependent) manner. tdTomato has codons varied to reduce recombination. Using bGHpA signal.

Antibodies from Article