Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation.
Ma J, Lindquist S
Proc Natl Acad Sci U S A 2001 Dec 18;98(26):14955-60. Epub 2001 Dec 11.
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Plasmids from Article
ID | Plasmid | Purpose |
---|---|---|
1319 | moPrP(3F4) D177N | |
1321 | cytosolic moPrP (3F4) | |
13917 | mSecPrP-pCB6+ |