Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders.
Kroupova A, Spiteri VA, Rutter ZJ, Furihata H, Darren D, Ramachandran S, Chakraborti S, Haubrich K, Pethe J, Gonzales D, Wijaya AJ, Rodriguez-Rios M, Sturbaut M, Lynch DM, Farnaby W, Nakasone MA, Zollman D, Ciulli A
Nat Commun. 2024 Oct 15;15(1):8885. doi: 10.1038/s41467-024-52871-9.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 215330 | His6-TEV-CRBN-midi | CRBN midi construct for use in crystallography and biophysical studies enabling ligand and degrader design |