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Deep mutational scans of XBB.1.5 and BQ.1.1 reveal ongoing epistatic drift during SARS-CoV-2 evolution.

Taylor AL, Starr TN
PLoS Pathog. 2023 Dec 29;19(12):e1011901. doi: 10.1371/journal.ppat.1011901. eCollection 2023 Dec. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
208085185_pETcon_SARS2_BQ1-1yeast surface display of the SARS-CoV-2 BQ.1.1 variant RBD
208086186_pETcon_SARS2_XBB1-5yeast surface display of the SARS-CoV-2 XBB.1.5 variant RBD

Antibodies from Article