An engineered AAV capsid mediates efficient transduction of pericytes and smooth muscle cells of the brain vasculature.
Ramirez SH, Hale J, McCarthy S, Cardenas CL, Dona K, Hanlon KS, Hudry E, De La Cruz D, Ng C, Das S, Nguyen DM, Nammour J, Bennett RE, Andrews A, Musolino PL, Maguire CA
Hum Gene Ther. 2023 Jun 27. doi: 10.1089/hum.2022.211. PubMed Article
Ramirez SH, Hale J, McCarthy S, Cardenas CL, Dona K, Hanlon KS, Hudry E, De La Cruz D, Ng C, Das S, Nguyen DM, Nammour J, Bennett RE, Andrews A, Musolino PL, Maguire CA
Hum Gene Ther. 2023 Jun 27. doi: 10.1089/hum.2022.211. PubMed Article
Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 197565 | AAV-PR rep/cap | encodes AAV-PR capsid that transduces pericytes and smooth muscle cells in mice after systemic delivery |