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Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses.

Cui C, Wang J, Fagerberg E, Chen PM, Connolly KA, Damo M, Cheung JF, Mao T, Askari AS, Chen S, Fitzgerald B, Foster GG, Eisenbarth SC, Zhao H, Craft J, Joshi NS
Cell. 2021 Dec 9;184(25):6101-6118.e13. doi: 10.1016/j.cell.2021.11.007. Epub 2021 Nov 30. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
202001pGK-HELLO LVExpresses HELLO neoantigen in tumor cells
202003pGK-HELLO-T2A-Cre LVGenerates lentiviral vector for autochthonous KP-HELLO tumor initiation by intratracheal administration to KP mice
202004LVEmpty lenti backbone

Antibodies from Article