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Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions.

Skinner OS, Blanco-Fernandez J, Goodman RP, Kawakami A, Shen H, Kemeny LV, Joesch-Cohen L, Rees MG, Roth JA, Fisher DE, Mootha VK, Jourdain AA
Nat Metab. 2023 May;5(5):765-776. doi: 10.1038/s42255-023-00774-2. Epub 2023 May 17. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
201590LENTICRISPR-ALDOA_sgRNA1CRISPR/Cas9-mediated gene knock-out
201591LENTICRISPR-ALDOA_sgRNA2CRISPR/Cas9-mediated gene knock-out
201594LENTICRISPR-GPI_sgRNA1CRISPR/Cas9-mediated gene knock-out
201595LENTICRISPR-GPI_sgRNA2CRISPR/Cas9-mediated gene knock-out
201616LENTICRISPR-PGM2_sgRNA1CRISPR/Cas9-mediated gene knock-out
201617LENTICRISPR-PGM2_sgRNA2CRISPR/Cas9-mediated gene knock-out
201618LENTICRISPR-RPE_sgRNA1CRISPR/Cas9-mediated gene knock-out
201619LENTICRISPR-RPE_sgRNA2CRISPR/Cas9-mediated gene knock-out
201624LENTICRISPR-TKT_sgRNA1CRISPR/Cas9-mediated gene knock-out
201625LENTICRISPR-TKT_sgRNA2CRISPR/Cas9-mediated gene knock-out
201628LENTICRISPR-TYMS_sgRNA1CRISPR/Cas9-mediated gene knock-out
201629LENTICRISPR-TYMS_sgRNA2CRISPR/Cas9-mediated gene knock-out
201630LENTICRISPR-UCK1_sgRNA1CRISPR/Cas9-mediated gene knock-out
201631LENTICRISPR-UCK1_sgRNA2CRISPR/Cas9-mediated gene knock-out
201632LENTICRISPR-UCK2_sgRNA1CRISPR/Cas9-mediated gene knock-out
201633LENTICRISPR-UCK2_sgRNA2CRISPR/Cas9-mediated gene knock-out
201634LENTICRISPR-UPP1_sgRNA1CRISPR/Cas9-mediated gene knock-out
201635LENTICRISPR-UPP1_sgRNA2CRISPR/Cas9-mediated gene knock-out
201639pWPI-GFP-3xFLAGOver-expression of 3xFLAG-tagged GFP
201644pWPI-UPP1-3xFLAGOver-expression of 3xFLAG-tagged human UPP1
201645pWPI-UPP2-3xFLAGOver-expression of 3xFLAG-tagged human UPP2

Antibodies from Article