Prostate-derived sterile 20-like kinases (PSKs/TAOKs) phosphorylate tau protein and are activated in tangle-bearing neurons in Alzheimer disease.
Tavares IA, Touma D, Lynham S, Troakes C, Schober M, Causevic M, Garg R, Noble W, Killick R, Bodi I, Hanger DP, Morris JD
J Biol Chem. 2013 May 24;288(21):15418-29. doi: 10.1074/jbc.M112.448183. Epub 2013 Apr 12.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 197123 | pRK5-Myc-PSK2 (1-416) | Expression of Myc-tagged PSK2 (aa1-416) / TAOK1 (aa1-416) in mammalian cells |
| 197124 | pRK5-Myc-PSK2 (1-416) (K57A) | Expression of kinase-deficient Myc-tagged PSK2 (aa1-416, K57A) / TAOK1 (aa1-416, K57A) in mammalian cells |