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PKC maturation is promoted by nucleotide pocket occupation independently of intrinsic kinase activity.

Cameron AJ, Escribano C, Saurin AT, Kostelecky B, Parker PJ
Nat Struct Mol Biol. 2009 Jun;16(6):624-30. doi: 10.1038/nsmb.1606. Epub 2009 May 24. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
195202GFP-PKCA WTMammalian expression vector for GFP tagged PKCA.
195203GFP-PKCA D463NMammalian expression vector for GFP tagged PKCA. Kinase-inactive mutant

Antibodies from Article