Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors.
Xu X, Masubuchi T, Cai Q, Zhao Y, Hui E
Elife. 2021 Nov 4;10. pii: 74276. doi: 10.7554/eLife.74276.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 180817 | pHR-PD-1 (BTLA ITIM)-mGFP | Expression of human PD-1 (BTLA ITIM) fused to mGFP |
| 180818 | pHR-BTLA (PD-1 ITIM)-mGFP | Expression of human BTLA (PD-1 ITIM) fused to mGFP |
| 180819 | pHR-PD-1 G224A-mGFP | Expression of human PD-1 G224A fused to mGFP |
| 180822 | pHR-SV40-mCherry-SHP1 (SHP2-cSH2) | Expression of N-terminal mCherry tagged human SHP1 with its cSH2 replaced by SHP2-cSH2 |
| 180823 | pHR-SV40-mCherry-SHP1 (SHP2-nSH2, cSH2) | Expression of N-terminal mCherry tagged human SHP1 with its nSH2 and cSH2 replaced by nSH2 and cSH2 of SHP2 |