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Sparse dictionary learning recovers pleiotropy from human cell fitness screens.

Pan J, Kwon JJ, Talamas JA, Borah AA, Vazquez F, Boehm JS, Tsherniak A, Zitnik M, McFarland JM, Hahn WC
Cell Syst. 2022 Jan 21. pii: S2405-4712(21)00488-9. doi: 10.1016/j.cels.2021.12.005. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
178534pLX_HAModifies pLX_317 backbone to express c-term HA tag (instead of c-term V5 tag)
178535pLX_HA-C7orf26v1Subcloned C7orf26v1 (ENST00000344417, Origene, RC219786L4) into pLX_HA backbone
178536pLX_HA-C7orf26v2Subcloned C7orf26v2 (ENST00000359073, Broad GPP TRCN0000477172) into pLX_HA backbone
178537pLX_317-C7orf26v1Subcloned C7orf26v1 (ENST00000344417, Origene, RC219786L4) into pLX_317 backbone

Antibodies from Article