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A novel transcription factor combination for direct reprogramming to a spontaneously contracting human cardiomyocyte-like state.

Romero-Tejeda M, Fonoudi H, Weddle CJ, DeKeyser JM, Lenny B, Fetterman KA, Magdy T, Sapkota Y, Epting C, Burridge PW
J Mol Cell Cardiol. 2023 Jul 6:S0022-2828(23)00106-2. doi: 10.1016/j.yjmcc.2023.06.005. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
170682tetO-AKT1doxycycline-inducible overexpression of AKT1
170683tetO-ESRRAdoxycycline-inducible overexpression of ESRRA
170684tetO-ESRRGdoxycycline-inducible overexpression of ESRRG
170685tetO-ETS2doxycycline-inducible overexpression of ETS2
170686tetO-FHL2doxycycline-inducible overexpression of FHL2
170687tetO-FOSL1doxycycline-inducible overexpression of FOSL1
170688tetO-GATA6doxycycline-inducible overexpression of GATA6
170689tetO-HAND1doxycycline-inducible overexpression of HAND1
170690tetO-HAND2doxycycline-inducible overexpression of HAND2
170691tetO-HEY2doxycycline-inducible overexpression of HEY2
170692tetO-ID1doxycycline-inducible overexpression of ID1
170693tetO-IRX5doxycycline-inducible overexpression of IRX5
170694tetO-MESP1doxycycline-inducible overexpression of MESP1
170695tetO-MITFdoxycycline-inducible overexpression of MITF
170696tetO-MYOCDdoxycycline-inducible overexpression of MYOCD
170697tetO-NFYBdoxycycline-inducible overexpression of NFYB
170698tetO-NR2F1doxycycline-inducible overexpression of NR2F1
170699tetO-PBX1doxycycline-inducible overexpression of PBX1
170700tetO-SMAD6doxycycline-inducible overexpression of SMAD6
170701tetO-SMARCD3doxycycline-inducible overexpression of SMARCD3
170702tetO-SNAI2doxycycline-inducible overexpression of SNAI2
170703tetO-SOX9doxycycline-inducible overexpression of SOX9
170704tetO-SRFdoxycycline-inducible overexpression of SRF
170705tetO-TBX20doxycycline-inducible overexpression of TBX20
170706tetO-TCF21doxycycline-inducible overexpression of TCF21
170707tetO-ZFPM2doxycycline-inducible overexpression of ZFPM2
170712pFU-GW-sMYH6-mNeon-TNNT2-mScarletdual fluorescent reporter for MYH6 (short) and TNNT2 promoters

Antibodies from Article