Designing a chemical inhibitor for the AAA protein spastin using active site mutations.
Cupido T, Pisa R, Kelley ME, Kapoor TM
Nat Chem Biol. 2019 May;15(5):444-452. doi: 10.1038/s41589-019-0225-6. Epub 2019 Feb 18.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 167542 | HA, EGFP Spastin M87 with exon 4 | For doxycycline inducible mammalian expression of EGFP tagged Spastin M87 with exon 4. |
| 167543 | HA, EGFP Spastin M87 with exon 4, N386C | For doxycycline inducible mammalian expression of EGFP tagged Spastin M87 with exon 4, with N386C mutation. |