Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa.
Wang SK, Xue Y, Rana P, Hong CM, Cepko CL
Proc Natl Acad Sci U S A. 2019 May 14;116(20):10140-10149. doi: 10.1073/pnas.1901787116. Epub 2019 Apr 29.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 164421 | AAV-hRedOpsin-fCX3CL1 | AAV plasmid expressing full-length CX3CL1 (fractalkine) in photoreceptors |
| 164422 | AAV-Best1-sCX3CL1 | AAV plasmid expressing soluble CX3CL1 (fractalkine) in retinal pigment epithelium |
| 164424 | AAV-Best1-sCD200 | AAV plasmid expressing soluble CD200 in retinal pigment epithelium |
| 164425 | AAV-hRedOpsin-fCD200 | AAV plasmid expressing full-length CD200 in photoreceptors |
| 164426 | AAV-hRedOpsin-mCherry | AAV plasmid expressing mCherry in photoreceptors |