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Modulation of metabolic functions through Cas13d-mediated gene knockdown in liver.

He B, Peng W, Huang J, Zhang H, Zhou Y, Yang X, Liu J, Li Z, Xu C, Xue M, Yang H, Huang P
Protein Cell. 2020 Mar 18. pii: 10.1007/s13238-020-00700-2. doi: 10.1007/s13238-020-00700-2. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
154002PB-U6-DR-SgRNA-DR-EF1a-mCherry-SV40Empty SgRNA expression system matching CasRx
154003AAV-EFS-NLS-CasRx-U6-DR-sgRNA_LacZ-DRVector expressed CasRx and sgRNA_LACZ for AAV package
154004PB-CAG-CasRX-P2A-EGFP-BGH PolyAExpress CasRx

Antibodies from Article