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Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia.

Cremer A, Ellegast JM, Alexe G, Frank ES, Ross L, Chu SH, Pikman Y, Robichaud A, Goodale A, Haupl B, Mohr S, Rao AV, Walker AR, Blachly JS, Piccioni F, Armstrong SA, Byrd JC, Oellerich T, Stegmaier K
Cancer Discov. 2020 Feb;10(2):214-231. doi: 10.1158/2159-8290.CD-19-0209. Epub 2019 Nov 26. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
140862pLX307/PTPN11 E76Gexpresses PTPN11 E76G
140939pLX307/PTPN11 T73Iexpresses PTPN11 T73I
140941pLX307/PTPN11expresses PTPN11

Antibodies from Article