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Cortical layer-specific critical dynamics triggering perception.

Marshel JH, Kim YS, Machado TA, Quirin S, Benson B, Kadmon J, Raja C, Chibukhchyan A, Ramakrishnan C, Inoue M, Shane JC, McKnight DJ, Yoshizawa S, Kato HE, Ganguli S, Deisseroth K
Science. 2019 Aug 9;365(6453). pii: science.aaw5202. doi: 10.1126/science.aaw5202. Epub 2019 Jul 18. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
130988pAAV-CaMKIIa-ChRmine-eYFP-WPREAAV vector to drive the expression of ChRmine-eYFP under the control of CamKIIa promoter
130989pAAV-CaMKIIa-ChRmine-eYFP-Kv2.1-WPREAAV vector to drive the expression of soma-targeted ChRmine-eYFP under the control of CamKIIa promoter
130990pAAV-CaMKIIa-ChRmine-mScarlet-WPREAAV vector to drive the expression of ChRmine-mScarlet under the control of CamKIIa promoter
130991pAAV-CaMKIIa-ChRmine-mScarlet-Kv2.1-WPREAAV vector to drive the expression of soma-targeted ChRmine-mScarlet under the control of CamKIIa promoter
130992pAAV-hSyn-ChRmine-eYFP-WPREAAV vector to drive the expression of ChRmine-eYFP under the control of human synapsin promoter
130993pAAV-hSyn-ChRmine-eYFP-Kv2.1-WPREAAV vector to drive the expression of soma-targeted ChRmine-eYFP under the control of human synapsin promoter
130994pAAV-hSyn-ChRmine-mScarlet-WPREAAV vector to drive the expression of ChRmine-mScarlet under the control of human synapsin promoter
130995pAAV-hSyn-ChRmine-mScarlet-Kv2.1-WPREAAV vector to drive the expression of soma-targeted ChRmine-mScarlet under the control of human synapsin promoter
130996pAAV-Ef1a-DIO ChRmine-eYFP-WPREDouble floxed ChRmine-eYFP under the control of Ef1a promoter
130997pAAV-Ef1a-DIO-ChRmine-eYFP-Kv2.1-WPREDouble floxed soma-targeted ChRmine-eYFP under the control of Ef1a promoter
130998pAAV-Ef1a-DIO-ChRmine-mScarlet-WPREDouble floxed ChRmine-mScarlet under the control of Ef1a promoter
130999pAAV-Ef1a-DIO-ChRmine-mScarlet-Kv2.1-WPREDouble floxed soma-targeted ChRmine-mScarlet under the control of Ef1a promoter
131000pAAV-CaMKIIa-mScarletAAV vector to drive the expression of mScarlet under the control of CamKIIa promoter
131001pAAV-hSyn-mScarletAAV vector to drive the expression of mScarlet under the control of human Synapsin promoter
131002pAAV-Ef1a-DIO mScarletDouble floxed mScarlet under the control of Ef1a promoter
131003pAAV-CaMKIIa-GCaMP 6m-p2A-ChRmine-Kv2.1-WPREbicistronic AAV vector to express GCaMP6m and soma-targeted ChRmine under the control of CamKIIa promoter
131004pAAV-hSyn-GCaMP 6m-p2A-ChRmine-Kv2.1-WPREbicistronic AAV vector to express GCaMP6m and soma-targeted ChRmine under the control of human Synapsin promoter

Antibodies from Article