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Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I.

Jain S, Hu C, Kluza J, Ke W, Tian G, Giurgiu M, Bleilevens A, Campos AR, Charbono A, Stickeler E, Maurer J, Holinski-Feder E, Vaisburg A, Bureik M, Luo G, Marchetti P, Cheng Y, Wolf DA
Cell Chem Biol. 2021 Nov 23. pii: S2451-9456(21)00479-7. doi: 10.1016/j.chembiol.2021.11.002. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
127486pcDNA3.1/NDUFS2/myc-HisExpresses myc-tagged NDUFS2 in mammalian cells
127487pcDNA3.1/NDUFS3/myc-HisExpresses myc-tagged NDUFS3 in mammalian cells
127488pcDNA3.1/NDUFS7/myc-HisExpresses myc-tagged NDUFS7 in mammalian cells
127489pcDNA3.1/NDUFS8/myc-HisExpresses myc-tagged NDUFS8 in mammalian cells
127490pcDNA3.1/NDUFV1/myc-HisExpresses myc-tagged NDUFV1 in mammalian cells
127491pcDNA3.1/NDUFV2/myc-HisExpresses myc-tagged NDUFV2 in mammalian cells
127492pcDNA3.1/NDUFS2 _2-33/myc-HisExpresses myc-tagged _MTS NDUFS2 in mammalian cells
127493pcDNA3.1/NDUFS2 _2-78/myc-HisExpresses myc-tagged _2-78 NDUFS2 in mammalian cells
127495pcDNA3.1/NDUFS2 _34-66/myc-HisExpresses myc-tagged _34-66 NDUFS2 in mammalian cells
127496pcDNA3.1/NDUFS2 _34-78/myc-HisExpresses myc-tagged _34-78 NDUFS2 in mammalian cells
127497pcDNA3.1/NDUFS2 E57A/myc-HisExpresses myc-tagged NDUFS2/E57A in mammalian cells
127498pcDNA3.1/NDUFS2 T58A/myc-HisExpresses myc-tagged NDUFS2/T58A in mammalian cells
127499pcDNA3.1/NDUFS2 H60A/myc-HisExpresses myc-tagged NDUFS2/H60A in mammalian cells
127500pcDNA3.1/NDUFS2 W61A/myc-HisExpresses myc-tagged NDUFS2/W61A in mammalian cells
127501pcDNA3.1/NDUFS2 K62A/myc-HisExpresses myc-tagged NDUFS2/K62A in mammalian cells
127502pcDNA3.1/NDUFS2 P63A/myc-HisExpresses myc-tagged NDUFS2/P63A in mammalian cells
127503pcDNA3.1/Ndi-1/myc-HisExpresses myc-tagged yeast Ndi-1 in mammalian cells

Antibodies from Article