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Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons.

Herdy J, Schafer S, Kim Y, Ansari Z, Zangwill D, Ku M, Paquola A, Lee H, Mertens J, Gage FH
Elife. 2019 May 17;8. pii: 41356. doi: 10.7554/eLife.41356. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
127289pLVX-UbC-rtTA-Ngn2:2A:Ascl1all-in-one inducible LV expression construct for Ngn2:2A:Ascl1 (aka UNA; for direct neuronal conversion)

Antibodies from Article