Androgen receptor exon 1 mutation causes androgen insensitivity by creating phosphorylation site and inhibiting melanoma antigen-A11 activation of NH2- and carboxyl-terminal interaction-dependent transactivation.
Lagarde WH, Blackwelder AJ, Minges JT, Hnat AT, French FS, Wilson EM
J Biol Chem. 2012 Mar 30;287(14):10905-15. doi: 10.1074/jbc.M111.336081. Epub 2012 Feb 13.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 126051 | pCMV-AR-R405S | Expresses human androgen receptor (R405S) in mammalian cells |
| 126052 | pCMV-AR-R405A | Expresses human androgen receptor (R405A) in mammalian cells |