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Ultra-specific and Amplification-free Quantification of Mutant DNA by Single-molecule Kinetic Fingerprinting.

Hayward SL, Lund PE, Kang Q, Johnson-Buck A, Tewari M, Walter NG
J Am Chem Soc. 2018 Aug 20. doi: 10.1021/jacs.8b06685. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
114719pUC19_4xT790M_28bp4 x 28 bp repeats of the EGFR T790M allele used as SiMREPS analyte standard
114720pUC19_4xT790_28bp4 x 28 bp repeats of the EGFR WT allele used as SiMREPS analyte standard
114721pUC19_T790M_28bp28 bp fragment of the EGFR T790M allele used as SiMREPS analyte standard
114722pUC19_T790_28bp28 bp fragment of the WT EGFR allele used as SiMREPS analyte standard

Antibodies from Article