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DNA-mediated dimerization on a compact sequence signature controls enhancer engagement and regulation by FOXA1.

Wang X, Srivastava Y, Jankowski A, Malik V, Wei Y, Del Rosario RC, Cojocaru V, Prabhakar S, Jauch R
Nucleic Acids Res. 2018 Jun 20;46(11):5470-5486. doi: 10.1093/nar/gky259. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
113350PVT1-luciferaseevaluate FOXA1 DIV motif enhancer activity near 50 kb of PVT1 gene
113351ESR1-luciferaseevaluate FOXA1 DIV motif enhancer activity near 50 kb of ESR1 gene
113352QSOX1-luciferaseevaluate FOXA1 DIV motif enhancer activity near 50 kb of QSOX1 gene
113353KAT6B-luciferaseevaluate FOXA1 DIV motif enhancer activity near 50 kb of KAT6B gene
113354ATP9A-luciferaseevaluate FOXA1 DIV motif enhancer activity near 50 kb of ATP9A gene
113355rs795-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs7957274 major allele (T)
113356rs795-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs7957274 minor allele (C)
113357rs699-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs6990531 major allele (T)
113358rs699-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs6990531 minor allele (G)
113359rs622-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs62288111 major allele (T)
113360rs622-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs62288111 minor allele (C)
113361rs700-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs7007731 major allele (C)
113362rs700-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs7007731 minor allele (T)
113363rs769-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs7697634 major allele (C)
113364rs769-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs7697634 minor allele (T)
113365rs344-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs34466261 major allele (AC)
113366rs344-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs34466261 minor allele (A)
113367rs117-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs11716984 major allele (A)
113368rs117-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs11716984 minor allele (T)
113369rs438-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs4384382 major allele (A)
113370rs438-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs4384382 minor allele (G)
113371rs281-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs281038 major allele (A)
113372rs281-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs281038 minor allele (G)
113373rs294-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs2941742 major allele (A)
113374rs294-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs2941742 minor allele (G)
113375rs676-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs67668514 major allele (A)
113376rs676-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs67668514 minor allele (-)
113377rs210-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs2104047 major allele (A)
113378rs210-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs2104047 minor allele (G)
113379rs214-majorevaluate FOXA1 DIV motif enhancer activity in SNP rs2149943 major allele (C)
113380rs214-minorevaluate FOXA1 DIV motif enhancer activity in SNP rs2149943 minor allele (T)
113381PVT1-Tol2evaluate FOXA1 DIV motif enhancer activity near 50 kb of PVT1 gene
113382ESR1-Tol2evaluate FOXA1 DIV motif enhancer activity near 50 kb of ESR1 gene
113383QSOX1-Tol2evaluate FOXA1 DIV motif enhancer activity near 50 kb of QSOX1 gene
113384KAT6B-Tol2evaluate FOXA1 DIV motif enhancer activity near 50 kb of KAT6B gene
113385ATP9A-Tol2evaluate FOXA1 DIV motif enhancer activity near 50 kb of ATP9A gene

Antibodies from Article