Flexible regions govern promiscuous binding of IL-24 to receptors IL-20R1 and IL-22R1.
Zahradnik J, Kolarova L, Peleg Y, Kolenko P, Svidenska S, Charnavets T, Unger T, Sussman JL, Schneider B
FEBS J. 2019 Oct;286(19):3858-3873. doi: 10.1111/febs.14945. Epub 2019 Jun 12.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 113072 | pSumo24P7 | Plasmid for highly efficient expression of engineered IL24 with mutated binding sites |
| 113073 | pSumo24P7vB4 | Plasmid for highly efficient expression of engineered IL24 with binding affinity to cognate receptors |