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CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair.

Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E, Boix C, Perrouault L, Tesson L, Geny S, De Cian A, Itier JM, Anegon I, Lopez B, Giovannangeli C, Concordet JP
Nat Commun. 2018 Mar 19;9(1):1133. doi: 10.1038/s41467-018-03475-7. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
109400pCas9-HEExpresses Cas9 fusion to HE (HDR-enhancer) domain of human CtIP protein
109401pCas9-GemininExpresses Cas9 fusion to Geminin degron domain
109402pCas9-HE-GemininExpresses Cas9 fusion to HE (HDR-enhancer) domain of human CtIP protein and Geminin degron
109403pCas9-CtIPExpresses Cas9 fusion to human CtIP protein

Antibodies from Article