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A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-kappaB Signaling.

Malty RH, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, Minic Z, Goebels F, Musso G, Wu Z, Abou-Tok H, Meyer M, Deineko V, Kassir S, Sidhu V, Jessulat M, Scott NE, Xiong X, Vlasblom J, Prasad B, Foster LJ, Alberio T, Garavaglia B, Yu H, Bader GD, Nakamura K, Parkinson J, Babu M
Cell Syst. 2017 Nov 7. pii: S2405-4712(17)30447-7. doi: 10.1016/j.cels.2017.10.010. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
83419pSOD1E133Δ-AcGFP1Expresses SOD1E133Δ in mammalian cells.
83441pSOD1E133insTT-AcGFP1Expresses SOD1E133insTT in mammalian cells.
83442pSOD1E133K-AcGFP1Expresses SOD1E133K in mammalian cells.
83444pLEX_307-SOD1WTMammalian expression of SOD1WT
83445pLEX_307-SOD1E133ΔMammalian expression of SOD1E133Δ.
83446pLEX_307-SOD1E133insTTMammalian expression of SOD1E133insTT.
83447pLEX_307-SOD1E133KMammalian expression of SOD1E133K
83478pPHAGE_DLD-H450A-C-TAPMammalian expression of the dehydrogenase-deficient mutant DLD-H450A.
83479pPHAGE_DLD-S456A-C-TAPMammalian expression of the proteolysis-deficient mutant DLD-S456A.
98688pLD-puro-Cc-PRDX5WT-VALentiviral expression of human PRDX5-WT in mammalian cells
98689pLD-puro-Cc-PRDX5E80K-VALentiviral expression of human PRDX5-E80K in mammalian cells
98690pLD-puro-Cc-PRDX5K83R-VALentiviral expression of human PRDX5-K83R in mammalian cells
98691pLD-puro-Cc-PRDX5K85R-VALentiviral expression of human PRDX5-K85R in mammalian cells
98692pENTR223-PRDX5E80KGateway cloning of human PRDX5-E80K
98693pENTR223-PRDX5K83RGateway cloning of human PRDX5-K83R
98694pENTR223-PRDX5K85RGateway cloning of human PRDX5-K85R

Antibodies from Article