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FXXLF and WXXLF sequences mediate the NH2-terminal interaction with the ligand binding domain of the androgen receptor.

He B, Kemppainen JA, Wilson EM
J Biol Chem. 2000 Jul 28;275(30):22986-94. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
89084pCMV-hAR-L26A,F27Amammalian expression of human androgen receptor with mutation of N-terminal FxxLF motif
89085pCMV-hAR-L26A,F27A,W433A,L436A,F437Amammalian expression of human androgen receptor with mutations of N-terminal FxxLF and WxxLF motifs
89086pCMV-hAR-W433A,L436A,F437Amammalian expression of human androgen receptor with mutations of N-terminal WxxLF motif
89089pCMV-hAR-F23Amammalian expression of human androgen receptor with mutation of N-terminal FxxLF motif
104192GST-AR-1-36Expresses human AR aa 1-36 in pGEX-5x-1 bact expression vector with GST
104193GST-AR-1-173Expresses human AR aa 1-173 in pGEX-5x-1 bacterial expression vector with GST
104194GST-AR-1-333Expresses human AR aa 1-333 in pGEX-5x-1 bacteral expression vector with GST
104195GST-AR-1-566Expresses human AR-1-566 from bacterial expression vector pGEX-5X-1 as GST fusion
104196GST-AR-1-660Expresses human AR-1-660 from bacterial expression vector pGEX-5X-1 as GST fusion protein
104197GST-AR-174-566Expresses human AR-174-566 in pGEX-3x bacterial expression vector as fusion protein with GST
104198GST-AR-334-566Expresses human AR-334-566 in pGEX-4T-1 bacterial expression vector as fusion protein with GST

Antibodies from Article