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TRAF2 suppresses basal IKK activity in resting cells and TNFalpha can activate IKK in TRAF2 and TRAF5 double knockout cells.

Zhang L, Blackwell K, Thomas GS, Sun S, Yeh WC, Habelhah H
J Mol Biol. 2009 Jun 12;389(3):495-510. doi: 10.1016/j.jmb.2009.04.054. Epub 2009 May 3. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
102679pBabe-puro-Flag-TRAF5retroviral expression plasmid for TRAF5

Antibodies from Article