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Systematic in vivo inactivation of chromatin regulating enzymes identifies Setd2 as a potent tumor suppressor in lung adenocarcinoma.

Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM
Cancer Res. 2017 Feb 15. pii: canres.2159.2016. doi: 10.1158/0008-5472.CAN-16-2159. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
82415LentiCRISPRv2CreLentiviral vector expressing Cre recombinase alongside Cas9 and an sgRNA cloning site
82416LentiCRISPRv2GFP3rd generation lentiviral vector expressing GFP alongside Cas9 and an sgRNA cloning site

Antibodies from Article