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The mycotoxin phomoxanthone A disturbs the form and function of the inner mitochondrial membrane.

Bohler P, Stuhldreier F, Anand R, Kondadi AK, Schlutermann D, Berleth N, Deitersen J, Wallot-Hieke N, Wu W, Frank M, Niemann H, Wesbuer E, Barbian A, Luyten T, Parys JB, Weidtkamp-Peters S, Borchardt A, Reichert AS, Pena-Blanco A, Garcia-Saez AJ, Itskanov S, van der Bliek AM, Proksch P, Wesselborg S, Stork B
Cell Death Dis. 2018 Feb 19;9(3):286. doi: 10.1038/s41419-018-0312-8. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
87379pMSCVpuro-Mito-DsRed1Retroviral transfection of cells to express DsRed1 (Ex555, Em585) localising to the mitochondrial matrix via the transit peptide from human TXN2 (Thioredoxin).
87381pMSCVpuro-Mito-PericamRetroviral transfection of cells to express ratiometric Pericam as described by Nagai et al 2001 (PMID 11248055) localising to the mitochondrial matrix via the transit peptide from human COX8A.

Antibodies from Article