Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.
Maiuri T, Mocle AJ, Hung CL, Xia J, van Roon-Mom WM, Truant R
Hum Mol Genet. 2016 Dec 25. pii: ddw395. doi: 10.1093/hmg/ddw395.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 97424 | nucHCB1 | Nuclear Huntingtin Chromobody 1: "Happ1" intrabody recognizing amino acids 41–81 of huntingtin, fused to eYFP and nuclear localization signal. |
| 98581 | nucHCB2 | Nuclear Huntingtin Chromobody 2: "iVHH4" intrabody recognizing amino acids 49–148 of huntingtin, fused to eYFP and nuclear localization signal. |
| 98582 | HCB1 | Huntingtin Chromobody 1: "Happ1" intrabody recognizing amino acids 41–81 of huntingtin, fused to eYFP. |
| 98583 | HCB2 | Huntingtin Chromobody 2: "iVHH4" intrabody recognizing amino acids 49-148 of huntingtin, fused to eYFP. |