Insulin promoter-driven Gaussia luciferase-based insulin secretion biosensor assay for discovery of beta-cell glucose-sensing pathways.
Kalwat MA, Wichaidit C, Nava Garcia AY, McCoy MK, McGlynn K, Hwang IH, MacMillan JB, Posner BA, Cobb MH
ACS Sens. 2016 Oct 28;1(10):1208-1212. Epub 2016 Oct 12.
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Plasmids from Article
| ID | Plasmid | Purpose |
|---|---|---|
| 89927 | pLenti-rInsp-hIns-GLuc | Expresses Insulin-GLuc from the rat insulin promoter. Gaussia Luc is inserted within the C-peptide and is co-secreted with insulin. |
| 89928 | pcDNA3.1+(rInsp)-Ins-GLuc | Expresses Insulin-GLuc from the rat insulin promoter. Gaussia Luc is inserted within the C-peptide and is co-secreted with insulin. |
| 89929 | pcDNA3.1+CMV-Ins-GLuc | Expresses Insulin-GLuc from the CMV promoter. Gaussia Luc is inserted within the C-peptide and is co-secreted with insulin. |