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A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy.

Feng Q, Snider L, Jagannathan S, Tawil R, van der Maarel SM, Tapscott SJ, Bradley RK
Elife. 2015 Jan 7;4. doi: 10.7554/eLife.04996. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
83967pRKB133_GI-DUX4-intron2(+)to test DUX4 mRNA is subjected to NMD upon intron2 inclusion
83968pRKB134_GI-DUX4-intron2(-)to test DUX4 mRNA is subjected to NMD upon intron2 inclusion

Antibodies from Article