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Targeted CNS Delivery Using Human MiniPromoters and Demonstrated Compatibility with Adeno-Associated Viral Vectors.

de Leeuw CN, Dyka FM, Boye SL, Laprise S, Zhou M, Chou AY, Borretta L, McInerny SC, Banks KG, Portales-Casamar E, Swanson MI, D'Souza CA, Boye SE, Jones SJ, Holt RA, Goldowitz D, Hauswirth WW, Wasserman WW, Simpson EM
Mol Ther Methods Clin Dev. 2014 Jan 8;1:5. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
29028pEMS1097Expression of the reporter gene under the control of the MiniPromoter in this plasmid has not been tested
29088pEMS1174Expression of the eGFP reporter gene was not detected in the brain and eye.
29104pEMS1207Expression of the eGFP reporter gene was not detected in the brain and eye.
29107pEMS1210Expression of the eGFP reporter gene was not detected in the brain and eye.
29109pEMS1215Expression of the eGFP reporter gene was not detected in the brain and eye.
29123pEMS1241Expression of the eGFP reporter gene was not detected in the brain and eye.
29194pEMS1396Expression of the eGFP reporter gene was not detected in the brain and eye.
29205pEMS1408Expression of the reporter gene under the control of the MiniPromoter in this plasmid has not been tested
29225pEMS1430Expression of the eGFP reporter gene was not detected in the brain and eye.
29235pEMS1482Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29236pEMS1485Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29237pEMS1486Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29241pEMS1493Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29242pEMS1494Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29246pEMS1498Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29247pEMS1499Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29248pEMS1500Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29265pEMS1568Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29270pEMS1593Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29279pEMS1617Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29283pEMS1641Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29290pEMS1673Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29295pEMS1707Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29296pEMS1710Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29297pEMS1712Pleiades (Ple) MiniPromoter expression pattern described in de Leeuw et al., MTM, 2014 (PMID: 24761428).
29299pEMS1503Homologous recombination plasmid for gene targeting at the mouse Hprt locus containing Ple32 (CLDN5 MiniPromoter) driving a lacZ reporter.

Antibodies from Article