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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.

Mazur PK, Reynoird N, Khatri P, Jansen PW, Wilkinson AW, Liu S, Barbash O, Van Aller GS, Huddleston M, Dhanak D, Tummino PJ, Kruger RG, Garcia BA, Butte AJ, Vermeulen M, Sage J, Gozani O
Nature. 2014 Jun 12;510(7504):283-7. doi: 10.1038/nature13320. Epub 2014 May 21. (Link opens in a new window) PubMed (Link opens in a new window) Article

Plasmids from Article

ID Plasmid Purpose
85650pMSCV-SMYD3retroviral expression of human SMYD3
85652pMSCV-MAP3K2retroviral expression of human MAP3K2
85654pSico shSMYD3-C humanexpression of shRNA targeting human SMYD3
85656pSico shMAP3K2 humanexpression of shRNA targeting human MAP3K2
85657pSico shMAP3K2 mouseexpression of shRNA targeting mouse MAP3K2

Antibodies from Article